5fwc: Difference between revisions

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'''Unreleased structure'''


The entry 5fwc is ON HOLD
==Human Spectrin SH3 domain D48G, E7A, K60A==
<StructureSection load='5fwc' size='340' side='right'caption='[[5fwc]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5fwc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FWC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5FWC FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5fwc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fwc OCA], [https://pdbe.org/5fwc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5fwc RCSB], [https://www.ebi.ac.uk/pdbsum/5fwc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5fwc ProSAT]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/SPTN1_HUMAN SPTN1_HUMAN] West syndrome. The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
[https://www.uniprot.org/uniprot/SPTN1_HUMAN SPTN1_HUMAN] Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.


Authors: Gallego, P., Navarro, S., Ventura, S., Reverter, D.
==See Also==
 
*[[Spectrin 3D structures|Spectrin 3D structures]]
Description: Human Spectrin SH3 domain D48G, E7A, K60A
__TOC__
[[Category: Unreleased Structures]]
</StructureSection>
[[Category: Gallego, P]]
[[Category: Homo sapiens]]
[[Category: Reverter, D]]
[[Category: Large Structures]]
[[Category: Navarro, S]]
[[Category: Gallego P]]
[[Category: Ventura, S]]
[[Category: Navarro S]]
[[Category: Reverter D]]
[[Category: Ventura S]]

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