2rkc: Difference between revisions

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-[[Image:2rkc.jpg|left|200px]]
-<!--
+==Crystal structure of the measles virus hemagglutinin==
-The line below this paragraph, containing "STRUCTURE_2rkc", creates the "Structure Box" on the page.
+<StructureSection load='2rkc' size='340' side='right'caption='[[2rkc]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[2rkc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Measles_morbillivirus Measles morbillivirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RKC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RKC FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-{{STRUCTURE_2rkc|  PDB=2rkc  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rkc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rkc OCA], [https://pdbe.org/2rkc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rkc RCSB], [https://www.ebi.ac.uk/pdbsum/2rkc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rkc ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/HEMA_MEASE HEMA_MEASE] Attaches the virus to cell receptors and thereby initiating infection. Binding of H protein to the receptor induces a conformational change that allows the F protein to trigger virion/cell membranes fusion. May use human CD46 and/or SLAMF1 as receptors for viral entry into the cell. The high degree of interaction between H and MCP/CD46 results in down-regulation of the latter from the surface of infected cells, rendering them more sensitive to c3b-mediated complement lysis.<ref>PMID:9811778</ref>
-'''Crystal structure of the measles virus hemagglutinin'''
+==See Also==
+*[[Hemagglutinin 3D structures|Hemagglutinin 3D structures]]
+== References ==
-==About this Structure==
+<references/>
-RKC is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Measles_virus Measles virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RKC OCA].
+__TOC__
-[[Category: Measles virus]]
+</StructureSection>
-[[Category: Single protein]]
+[[Category: Large Structures]]
-[[Category: Colf, L A.]]
+[[Category: Measles morbillivirus]]
-[[Category: Garcia, K C.]]
+[[Category: Colf LA]]
-[[Category: Juo, Z S.]]
+[[Category: Garcia KC]]
-[[Category: Envelope protein]]
+[[Category: Juo ZS]]
-[[Category: Hemagglutinin]]
-[[Category: Measles virus]]
-[[Category: Membrane]]
-[[Category: Transmembrane]]
-[[Category: Viral protein]]
-[[Category: Virion]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 17:04:39 2008''