5fdx: Difference between revisions

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-'''Unreleased structure'''
-The entry 5fdx is ON HOLD  until Paper Publication
+==Structure of DDR1 receptor tyrosine kinase in complex with D2164 inhibitor at 2.65 Angstroms resolution.==
+<StructureSection load='5fdx' size='340' side='right'caption='[[5fdx]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5fdx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FDX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5FDX FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5X1:3-[(4-METHYLPIPERAZIN-1-YL)METHYL]-~{N}-[(4~{R})-4-METHYL-2-PYRIMIDIN-5-YL-3,4-DIHYDRO-1~{H}-ISOQUINOLIN-7-YL]-5-(TRIFLUOROMETHYL)BENZAMIDE'>5X1</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5fdx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fdx OCA], [https://pdbe.org/5fdx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5fdx RCSB], [https://www.ebi.ac.uk/pdbsum/5fdx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5fdx ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/DDR1_HUMAN DDR1_HUMAN]
-Authors: BARTUAL, S.G., PINKAS, D.M., WANG, Z., DING, K., Mahajan, P., KUPINSKA, K., Mukhopadhyay, S., Strain-Damerell, C., Chalk, R., Borkowska, O., Talon, R., Kopec, J., Williams, E., Tallant, C., Chaikuad, A., Sorell, F., Newman, J., Burgess-Brown, N., VON DELFT, F., Arrowsmith, C.H., Edwards, A.M., BOUNTRA, C., BULLOCK, A., Structural Genomics Consortium (SGC)
+==See Also==
+*[[Epithelial discoidin domain-containing receptor|Epithelial discoidin domain-containing receptor]]
-Description: Structure of DDR1 receptor tyrosine kinase in complex with D2164 inhibitor at 2.65 Angstroms resolution.
+__TOC__
-[[Category: Unreleased Structures]]
+</StructureSection>
-[[Category: Bullock, A]]
+[[Category: Homo sapiens]]
-[[Category: Chaikuad, A]]
+[[Category: Large Structures]]
-[[Category: Sorell, F]]
+[[Category: Arrowsmith CH]]
-[[Category: Burgess-Brown, N]]
+[[Category: Bartual SG]]
-[[Category: Borkowska, O]]
+[[Category: Borkowska O]]
-[[Category: Pinkas, D.M]]
+[[Category: Bountra C]]
-[[Category: Newman, J]]
+[[Category: Bullock A]]
-[[Category: Mukhopadhyay, S]]
+[[Category: Burgess-Brown N]]
-[[Category: Ding, K]]
+[[Category: Chaikuad A]]
-[[Category: Wang, Z]]
+[[Category: Chalk R]]
-[[Category: Bountra, C]]
+[[Category: Ding K]]
-[[Category: Bartual, S.G]]
+[[Category: Edwards AM]]
-[[Category: Kupinska, K]]
+[[Category: Kopec J]]
-[[Category: Arrowsmith, C.H]]
+[[Category: Kupinska K]]
-[[Category: Chalk, R]]
+[[Category: Mahajan P]]
-[[Category: Williams, E]]
+[[Category: Mukhopadhyay S]]
-[[Category: Kopec, J]]
+[[Category: Newman J]]
-[[Category: Von Delft, F]]
+[[Category: Pinkas DM]]
-[[Category: Mahajan, P]]
+[[Category: Sorell F]]
-[[Category: Edwards, A.M]]
+[[Category: Strain-Damerell C]]
-[[Category: Talon, R]]
+[[Category: Tallant C]]
-[[Category: Structural Genomics Consortium (Sgc)]]
+[[Category: Talon R]]
-[[Category: Tallant, C]]
+[[Category: Wang Z]]
-[[Category: Strain-Damerell, C]]
+[[Category: Williams E]]
+[[Category: Von Delft F]]