5fdx: Difference between revisions

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New page: '''Unreleased structure''' The entry 5fdx is ON HOLD until Paper Publication Authors: BARTUAL, S.G., PINKAS, D.M., WANG, Z., DING, K., Mahajan, P., KUPINSKA, K., Mukhopadhyay, S., Strai...
 
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'''Unreleased structure'''


The entry 5fdx is ON HOLD  until Paper Publication
==Structure of DDR1 receptor tyrosine kinase in complex with D2164 inhibitor at 2.65 Angstroms resolution.==
<StructureSection load='5fdx' size='340' side='right'caption='[[5fdx]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5fdx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FDX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5FDX FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5X1:3-[(4-METHYLPIPERAZIN-1-YL)METHYL]-~{N}-[(4~{R})-4-METHYL-2-PYRIMIDIN-5-YL-3,4-DIHYDRO-1~{H}-ISOQUINOLIN-7-YL]-5-(TRIFLUOROMETHYL)BENZAMIDE'>5X1</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5fdx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fdx OCA], [https://pdbe.org/5fdx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5fdx RCSB], [https://www.ebi.ac.uk/pdbsum/5fdx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5fdx ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DDR1_HUMAN DDR1_HUMAN]


Authors: BARTUAL, S.G., PINKAS, D.M., WANG, Z., DING, K., Mahajan, P., KUPINSKA, K., Mukhopadhyay, S., Strain-Damerell, C., Chalk, R., Borkowska, O., Talon, R., Kopec, J., Williams, E., Tallant, C., Chaikuad, A., Sorell, F., Newman, J., Burgess-Brown, N., VON DELFT, F., Arrowsmith, C.H., Edwards, A.M., BOUNTRA, C., BULLOCK, A., Structural Genomics Consortium (SGC)
==See Also==
 
*[[Epithelial discoidin domain-containing receptor|Epithelial discoidin domain-containing receptor]]
Description: Structure of DDR1 receptor tyrosine kinase in complex with D2164 inhibitor at 2.65 Angstroms resolution.
__TOC__
[[Category: Unreleased Structures]]
</StructureSection>
[[Category: Bullock, A]]
[[Category: Homo sapiens]]
[[Category: Chaikuad, A]]
[[Category: Large Structures]]
[[Category: Sorell, F]]
[[Category: Arrowsmith CH]]
[[Category: Burgess-Brown, N]]
[[Category: Bartual SG]]
[[Category: Borkowska, O]]
[[Category: Borkowska O]]
[[Category: Pinkas, D.M]]
[[Category: Bountra C]]
[[Category: Newman, J]]
[[Category: Bullock A]]
[[Category: Mukhopadhyay, S]]
[[Category: Burgess-Brown N]]
[[Category: Ding, K]]
[[Category: Chaikuad A]]
[[Category: Wang, Z]]
[[Category: Chalk R]]
[[Category: Bountra, C]]
[[Category: Ding K]]
[[Category: Bartual, S.G]]
[[Category: Edwards AM]]
[[Category: Kupinska, K]]
[[Category: Kopec J]]
[[Category: Arrowsmith, C.H]]
[[Category: Kupinska K]]
[[Category: Chalk, R]]
[[Category: Mahajan P]]
[[Category: Williams, E]]
[[Category: Mukhopadhyay S]]
[[Category: Kopec, J]]
[[Category: Newman J]]
[[Category: Von Delft, F]]
[[Category: Pinkas DM]]
[[Category: Mahajan, P]]
[[Category: Sorell F]]
[[Category: Edwards, A.M]]
[[Category: Strain-Damerell C]]
[[Category: Talon, R]]
[[Category: Tallant C]]
[[Category: Structural Genomics Consortium (Sgc)]]
[[Category: Talon R]]
[[Category: Tallant, C]]
[[Category: Wang Z]]
[[Category: Strain-Damerell, C]]
[[Category: Williams E]]
[[Category: Von Delft F]]

Latest revision as of 09:47, 19 July 2023

Structure of DDR1 receptor tyrosine kinase in complex with D2164 inhibitor at 2.65 Angstroms resolution.Structure of DDR1 receptor tyrosine kinase in complex with D2164 inhibitor at 2.65 Angstroms resolution.

Structural highlights

5fdx is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.65Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

DDR1_HUMAN

See Also

5fdx, resolution 2.65Å

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OCA
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