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==Crystal Structure of Metallothiol Transferase from Bacillus anthracis str. Ames== | ==Crystal Structure of Metallothiol Transferase from Bacillus anthracis str. Ames== | ||
<StructureSection load='5f6q' size='340' side='right' caption='[[5f6q]], [[Resolution|resolution]] 1.52Å' scene=''> | <StructureSection load='5f6q' size='340' side='right'caption='[[5f6q]], [[Resolution|resolution]] 1.52Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5f6q]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5F6Q OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[5f6q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5F6Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5F6Q FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.52Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5f6q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5f6q OCA], [https://pdbe.org/5f6q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5f6q RCSB], [https://www.ebi.ac.uk/pdbsum/5f6q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5f6q ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/FOSB2_BACAN FOSB2_BACAN] Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor.[HAMAP-Rule:MF_01512] | ||
==See Also== | |||
*[[Metallothiol transferase FosB|Metallothiol transferase FosB]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Bacillus anthracis]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Joachimiak | [[Category: Anderson WF]] | ||
[[Category: Kim | [[Category: Joachimiak A]] | ||
[[Category: Maltseva | [[Category: Kim Y]] | ||
[[Category: Osipiuk | [[Category: Maltseva N]] | ||
[[Category: Osipiuk J]] | |||
Latest revision as of 09:40, 19 July 2023
Crystal Structure of Metallothiol Transferase from Bacillus anthracis str. AmesCrystal Structure of Metallothiol Transferase from Bacillus anthracis str. Ames
Structural highlights
FunctionFOSB2_BACAN Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor.[HAMAP-Rule:MF_01512] See Also |
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