3lon: Difference between revisions
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New page: '''Unreleased structure''' The entry 3lon is ON HOLD Authors: Arasappan, A., Bennett F., Bogen, S. L., Blackman, M., Chen, K., Hendrata, S.,Huang,Y., Huelgas,R. M.,Nair, L., Padilla, A.... |
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==HCV NS3-4a protease domain with ketoamide inhibitor narlaprevir== | |||
<StructureSection load='3lon' size='340' side='right'caption='[[3lon]], [[Resolution|resolution]] 2.20Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3lon]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Hepatitis_C_virus_genotype_1a Hepatitis C virus genotype 1a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LON OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LON FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=NNA:(1R,2S,5S)-3-[N-({1-[(tert-butylsulfonyl)methyl]cyclohexyl}carbamoyl)-3-methyl-L-valyl]-N-{(1S)-1-[(1R)-2-(cyclopropylamino)-1-hydroxy-2-oxoethyl]pentyl}-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide'>NNA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lon FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lon OCA], [https://pdbe.org/3lon PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lon RCSB], [https://www.ebi.ac.uk/pdbsum/3lon PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lon ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/Q9ELS8_9HEPC Q9ELS8_9HEPC] | |||
==See Also== | |||
*[[Virus protease 3D structures|Virus protease 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Hepatitis C virus genotype 1a]] | |||
[[Category: Large Structures]] | |||
[[Category: Prongay AJ]] | |||
Latest revision as of 09:36, 19 July 2023
HCV NS3-4a protease domain with ketoamide inhibitor narlaprevirHCV NS3-4a protease domain with ketoamide inhibitor narlaprevir
Structural highlights
FunctionSee Also |
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