Neuroligin: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

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 *'''NLGN-1''' regulates spines and synaptic plasticity<ref>PMID:26880202</ref>. <br />
 *'''NLGN-2''' is localized to inhibitory synapses<ref>PMID:15540461</ref>. <br />
+*'''NLGN-3''' is a synapse organizer which shapes normal function and autism disorder<ref>PMID:17897391</ref>. <br />
 *'''NLGN-4''' is localized to glyceric  post-synapses and regulates retina inhibition<ref>PMID:21282647</ref>. <br />
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 == Structural insights ==
-The <scene name='42/422448/Cv/4'>NLGN-NRXN complex involves the octahedrally coordinated Ca+2 ion</scene><ref>PMID:18084303</ref>. Water molecules shown as red spheres.
+The <scene name='42/422448/Cv/5'>NLGN-NRXN complex involves the octahedrally coordinated Ca+2 ion</scene><ref>PMID:18084303</ref>. Water molecules are shown as red spheres.
 </StructureSection>
 == 3D Structures of Neuroligin ==
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 **[[5ojk]] -  hNLGN-1 cholinesterase domain - human<br />
 **[[3bix]] -  rNLGN-1 cholinesterase domain - rat<br />
+**[[8gs4]] -  hNLGN-2 – Cryo EM<br />
 **[[3bl8]] -  mNLGN-2 cholinesterase domain – mouse<br />
+**[[7cee]] - mNLGN-3 cholinesterase domain<br />
 **[[3be8]] -  hNLGN-4 cholinesterase domain – human<br />
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 **[[5v5v]] -  rNLGN-2 cholinesterase domain + MDGA1<br />
 **[[5xeq]] -  rNLGN-2 cholinesterase domain (mutant) + MDGA1<br />
+**[[7ceg]] -  mNLGN-3 cholinesterase domain + PTP d<br />
 }}