5f5k: Difference between revisions

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==E.Coli GlpG Y205F mutant complexed with aldehyde inhibitor in DMPC/CHAPSO bicelle==
==E.Coli GlpG Y205F mutant complexed with aldehyde inhibitor in DMPC/CHAPSO bicelle==
<StructureSection load='5f5k' size='340' side='right' caption='[[5f5k]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
<StructureSection load='5f5k' size='340' side='right'caption='[[5f5k]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5f5k]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5F5K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5F5K FirstGlance]. <br>
<table><tr><td colspan='2'>[[5f5k]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster] and [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5F5K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5F5K FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=5XU:(2~{S})-2-AZANYLPROPANAL'>5XU</scene>, <scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5f5b|5f5b]], [[5f5d|5f5d]], [[5f5g|5f5g]], [[5f5j|5f5j]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5XU:(2~{S})-2-AZANYLPROPANAL'>5XU</scene>, <scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Rhomboid_protease Rhomboid protease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.105 3.4.21.105] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5f5k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5f5k OCA], [https://pdbe.org/5f5k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5f5k RCSB], [https://www.ebi.ac.uk/pdbsum/5f5k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5f5k ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5f5k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5f5k OCA], [http://pdbe.org/5f5k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5f5k RCSB], [http://www.ebi.ac.uk/pdbsum/5f5k PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/A0A0J2E248_ECOLX A0A0J2E248_ECOLX]] Rhomboid-type serine protease that catalyzes intramembrane proteolysis.[HAMAP-Rule:MF_01594]
[https://www.uniprot.org/uniprot/GLPG_ECOLI GLPG_ECOLI] Rhomboid-type serine protease that catalyzes intramembrane proteolysis.<ref>PMID:17099694</ref> <ref>PMID:16216077</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5f5k" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5f5k" style="background-color:#fffaf0;"></div>
==See Also==
*[[Rhomboid protease|Rhomboid protease]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Rhomboid protease]]
[[Category: Drosophila melanogaster]]
[[Category: Cho, S]]
[[Category: Escherichia coli]]
[[Category: Dickey, S W]]
[[Category: Large Structures]]
[[Category: Urban, S]]
[[Category: Cho S]]
[[Category: Aldehyde inhibitor]]
[[Category: Dickey SW]]
[[Category: Bicelle]]
[[Category: Urban S]]
[[Category: Glpg]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Intramembrane protease]]
[[Category: Rhomboid]]

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