5esh: Difference between revisions

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-'''Unreleased structure'''
-The entry 5esh is ON HOLD  until Paper Publication
+==Saccharomyces cerevisiae CYP51 (Lanosterol 14-alpha demethylase) G73W mutant in complex with itraconazole==
+<StructureSection load='5esh' size='340' side='right'caption='[[5esh]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5esh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_YJM789 Saccharomyces cerevisiae YJM789]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ESH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ESH FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1YN:2-[(2R)-BUTAN-2-YL]-4-{4-[4-(4-{[(2R,4S)-2-(2,4-DICHLOROPHENYL)-2-(1H-1,2,4-TRIAZOL-1-YLMETHYL)-1,3-DIOXOLAN-4-YL]METHOXY}PHENYL)PIPERAZIN-1-YL]PHENYL}-2,4-DIHYDRO-3H-1,2,4-TRIAZOL-3-ONE'>1YN</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5esh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5esh OCA], [https://pdbe.org/5esh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5esh RCSB], [https://www.ebi.ac.uk/pdbsum/5esh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5esh ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/A6ZSR0_YEAS7 A6ZSR0_YEAS7]
-Authors: Sagatova, A., Keniya, M.V., Wilson, R.K., Sabherwal, M., Tyndall, J.D.A., Monk, B.C.
+==See Also==
+*[[Cytochrome P450 3D structures|Cytochrome P450 3D structures]]
-Description: Saccharomyces cerevisiae CYP51 (Lanosterol 14-alpha demethylase) G73W mutant in complex with itraconazole
+__TOC__
-[[Category: Unreleased Structures]]
+</StructureSection>
-[[Category: Tyndall, J.D.A]]
+[[Category: Large Structures]]
-[[Category: Sabherwal, M]]
+[[Category: Saccharomyces cerevisiae YJM789]]
-[[Category: Wilson, R.K]]
+[[Category: Keniya MV]]
-[[Category: Sagatova, A]]
+[[Category: Monk BC]]
-[[Category: Monk, B.C]]
+[[Category: Sabherwal M]]
-[[Category: Keniya, M.V]]
+[[Category: Sagatova A]]
+[[Category: Tyndall JDA]]
+[[Category: Wilson RK]]