5eq6: Difference between revisions

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 ==Pseudomonas aeruginosa PilM bound to AMP-PNP==
-<StructureSection load='5eq6' size='340' side='right' caption='[[5eq6]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
+<StructureSection load='5eq6' size='340' side='right'caption='[[5eq6]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[5eq6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseae Pseae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EQ6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EQ6 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[5eq6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EQ6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5EQ6 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.5&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5eox|5eox]], [[5eoy|5eoy]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pilM, PA5044 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 PSEAE])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5eq6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eq6 OCA], [https://pdbe.org/5eq6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5eq6 RCSB], [https://www.ebi.ac.uk/pdbsum/5eq6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5eq6 ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5eq6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eq6 OCA], [http://pdbe.org/5eq6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5eq6 RCSB], [http://www.ebi.ac.uk/pdbsum/5eq6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5eq6 ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/PILM_PSEAE PILM_PSEAE] Inner membrane component of the type IV (T4S) secretion system that plays a role in surface and host cell adhesion, colonization, biofilm maturation, virulence, and twitching, a form of surface-associated motility. PilN/PilO heterodimers form the foundation of the inner-membrane PilM/PilN/PilO/PilP complex which plays an essential role in the assembly of a functional T4 pilus (PubMed:19857645, PubMed:19857646). In turn, associates with PilN and facilitates PilM functionally relevant structural changes that differentially impacts PilM binding to PilB, PilT, and PilC (PubMed:27022027).<ref>PMID:19857645</ref> <ref>PMID:19857646</ref> <ref>PMID:27022027</ref>
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 22: / Line 23: @@
 __TOC__
 </StructureSection>
-[[Category: Pseae]]
+[[Category: Large Structures]]
-[[Category: Burrows, L L]]
+[[Category: Pseudomonas aeruginosa PAO1]]
-[[Category: Calmettes, C]]
+[[Category: Burrows LL]]
-[[Category: Howell, P L]]
+[[Category: Calmettes C]]
-[[Category: McCallum, M]]
+[[Category: Howell PL]]
-[[Category: Moraes, T]]
+[[Category: McCallum M]]
-[[Category: Robinson, H]]
+[[Category: Moraes T]]
-[[Category: Shah, M]]
+[[Category: Robinson H]]
-[[Category: Tammam, S]]
+[[Category: Shah M]]
-[[Category: Hsp70-like]]
+[[Category: Tammam S]]
-[[Category: Peptide binding protein]]
-[[Category: Pilm]]
-[[Category: T4p]]
-[[Category: Type iv pilus]]