NADP-dependent malic enzyme: Difference between revisions
Michal Harel (talk | contribs) No edit summary |
Michal Harel (talk | contribs) No edit summary |
||
| (4 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
<StructureSection load=' | <StructureSection load='3wja' size='340' side='right' caption='The best structure for NADP-dependent malic enzyme shown: [[3wja]]' scene=''> | ||
Best example is PDB entry [[3wja]] and is shown in the viewer.<br> | Best example is PDB entry [[3wja]] and is shown in the viewer.<br> | ||
==Catalytic Activity == | ==Catalytic Activity == | ||
Oxaloacetate = pyruvate + CO(2).Data source: Uniprot [http://www.uniprot.org/uniprot/P48163 P48163]<br> | Oxaloacetate = pyruvate + CO(2).Data source: Uniprot [http://www.uniprot.org/uniprot/P48163 P48163]<br> | ||
Or | Or the decarboxylation of malate to pyruvate<ref>PMID:8187880</ref>. | ||
== Biological process == | == Biological process == | ||
| Line 30: | Line 30: | ||
***2.5 A resolution | ***2.5 A resolution | ||
== Alternative names for NADP-dependent malic enzyme == | == Alternative names for NADP-dependent malic enzyme == | ||
Molecule NADP-dependent malic enzyme, also known as NADP-ME, NADP-dependent malic enzyme and Malic enzyme 1. | Molecule '''NADP-dependent malic enzyme''', also known as '''NADP-ME''', '''NADP-dependent malic enzyme''' and '''Malic enzyme 1'''. | ||
== 3D Structures of NADP-dependent malic enzyme == | |||
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | |||
[[3wja]], [[2aw5]] – hME - human<br /> | |||
[[7x11]], [[7x12]] – hME1 + NADP<br /> | |||
[[8e76]], [[8eyn]] – hME3<br /> | |||
[[8e78]], [[8e8o]], [[8eyo]] – hME3 + NADP<br /> | |||
[[1gq2]] – ME + NADP - pigeon<br /> | |||
[[5ou5]] – ME - maize<br /> | |||
== References == | |||
<references/> | |||
[[Category:Topic Page]][[Category:PDBe]] | [[Category:Topic Page]][[Category:PDBe]] | ||
Latest revision as of 12:11, 11 July 2023
<StructureSection load='3wja' size='340' side='right' caption='The best structure for NADP-dependent malic enzyme shown: 3wja' scene=>
Best example is PDB entry 3wja and is shown in the viewer.
Catalytic ActivityCatalytic Activity
Oxaloacetate = pyruvate + CO(2).Data source: Uniprot P48163
Or the decarboxylation of malate to pyruvate[1].
Biological processBiological process
Is involved in the following biological processes:
malate metabolic process
oxidation-reduction process
response to carbohydrate
response to hormone
carbohydrate metabolic process
protein tetramerization
regulation of NADP metabolic process
NADP biosynthetic process
small molecule metabolic process
cellular lipid metabolic process
In structuresIn structures
NADP-dependent malic enzyme is found in 3 PDB entries
- Eukaryota (3 PDB entries):
- Homo sapiens (2 PDB entries):
- 3wja
- Title: The crystal structure of human cytosolic NADP(+)-dependent malic enzyme in apo form
- 2.548 A resolution
- Search the PDB for NADP-dependent malic enzyme from Homo sapiens
- Columba livia (1 PDB entries):
- 1gq2
- Title: MALIC ENZYME FROM PIGEON LIVER
- 2.5 A resolution
- Homo sapiens (2 PDB entries):
Alternative names for NADP-dependent malic enzymeAlternative names for NADP-dependent malic enzyme
Molecule NADP-dependent malic enzyme, also known as NADP-ME, NADP-dependent malic enzyme and Malic enzyme 1.
3D Structures of NADP-dependent malic enzyme3D Structures of NADP-dependent malic enzyme
Updated on 11-July-2023
3wja, 2aw5 – hME - human
7x11, 7x12 – hME1 + NADP
8e76, 8eyn – hME3
8e78, 8e8o, 8eyo – hME3 + NADP
1gq2 – ME + NADP - pigeon
5ou5 – ME - maize