NADP-dependent malic enzyme: Difference between revisions

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<StructureSection load='3wja' size='340' side='right' caption='The best structure for NADP-dependent malic enzyme shown: 3wja' scene=''>
<StructureSection load='3wja' size='340' side='right' caption='The best structure for NADP-dependent malic enzyme shown: [[3wja]]' scene=''>
Best example is PDB entry [[3wja]] and is shown in the viewer.<br>
Best example is PDB entry [[3wja]] and is shown in the viewer.<br>
Molecule NADP-dependent malic enzyme, also known as NADP-ME, NADP-dependent malic enzyme and Malic enzyme 1.
==Catalytic Activity ==
==Catalytic Activity ==
Oxaloacetate = pyruvate + CO(2).Data source: Uniprot [http://www.uniprot.org/uniprot/P48163 P48163]<br>
Oxaloacetate = pyruvate + CO(2).Data source: Uniprot [http://www.uniprot.org/uniprot/P48163 P48163]<br>
Or the decarboxylation of malate to pyruvate<ref>PMID:8187880</ref>.


== Disease ==
== Relevance ==
== Structural highlights ==
== Biological process ==
== Biological process ==
Is involved in the following biological processes:<br>
Is involved in the following biological processes:<br>
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***Title: The crystal structure of human cytosolic NADP(+)-dependent malic enzyme in apo form
***Title: The crystal structure of human cytosolic NADP(+)-dependent malic enzyme in apo form
***2.548 A resolution
***2.548 A resolution
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Homo%20sapiens%22&all_molecule_names:%22NADP-dependent%20malic%20enzyme%22&!chimera:y Search for other PDB entries]
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Homo%20sapiens%22&all_molecule_names:%22NADP-dependent%20malic%20enzyme%22&!chimera:y Search the PDB for NADP-dependent malic enzyme from Homo sapiens]
**<b>Columba livia</b> (1 PDB entries): <br>
**<b>Columba livia</b> (1 PDB entries): <br>
***[[1gq2]] <div class="pdb-prints 1gq2"></div>
***[[1gq2]] <div class="pdb-prints 1gq2"></div>
***Title: MALIC ENZYME FROM PIGEON LIVER
***Title: MALIC ENZYME FROM PIGEON LIVER
***2.5 A resolution
***2.5 A resolution
== Alternative names for NADP-dependent malic enzyme ==
Molecule '''NADP-dependent malic enzyme''', also known as '''NADP-ME''', '''NADP-dependent malic enzyme''' and '''Malic enzyme 1'''.
== 3D Structures of NADP-dependent malic enzyme ==
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
[[3wja]], [[2aw5]] – hME - human<br />
[[7x11]], [[7x12]] – hME1 + NADP<br />
[[8e76]], [[8eyn]] – hME3<br />
[[8e78]], [[8e8o]], [[8eyo]] – hME3 + NADP<br />
[[1gq2]] – ME + NADP - pigeon<br />
[[5ou5]] – ME - maize<br />
== References ==
<references/>
[[Category:Topic Page]][[Category:PDBe]]
[[Category:Topic Page]][[Category:PDBe]]

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PDBe, Jaime Prilusky, Michal Harel