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==Human mitochondrial tryptophanyl-tRNA synthetase bound by indolmycin and Mn*ATP.==
==Human mitochondrial tryptophanyl-tRNA synthetase bound by indolmycin and Mn*ATP.==
<StructureSection load='5ekd' size='340' side='right' caption='[[5ekd]], [[Resolution|resolution]] 1.82&Aring;' scene=''>
<StructureSection load='5ekd' size='340' side='right'caption='[[5ekd]], [[Resolution|resolution]] 1.82&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5ekd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EKD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EKD FirstGlance]. <br>
<table><tr><td colspan='2'>[[5ekd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EKD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5EKD FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5BX:(5S)-5-[(1R)-1-(1H-INDOL-3-YL)ETHYL]-2-(METHYLAMINO)-1,3-OXAZOL-4(5H)-ONE'>5BX</scene>, <scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.82&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">WARS2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5BX:(5S)-5-[(1R)-1-(1H-INDOL-3-YL)ETHYL]-2-(METHYLAMINO)-1,3-OXAZOL-4(5H)-ONE'>5BX</scene>, <scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Tryptophan--tRNA_ligase Tryptophan--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.2 6.1.1.2] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ekd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ekd OCA], [https://pdbe.org/5ekd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ekd RCSB], [https://www.ebi.ac.uk/pdbsum/5ekd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ekd ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ekd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ekd OCA], [http://pdbe.org/5ekd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ekd RCSB], [http://www.ebi.ac.uk/pdbsum/5ekd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ekd ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SYWM_HUMAN SYWM_HUMAN]
==See Also==
*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Tryptophan--tRNA ligase]]
[[Category: Large Structures]]
[[Category: Carter, C W]]
[[Category: Carter Jr CW]]
[[Category: Williams, T L]]
[[Category: Williams TL]]
[[Category: Complex]]
[[Category: Indolmycin]]
[[Category: Ligase-antibiotic complex]]
[[Category: Mitochondrial]]
[[Category: Trpr]]

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