5e7v: Difference between revisions
No edit summary |
No edit summary |
||
| (One intermediate revision by the same user not shown) | |||
| Line 1: | Line 1: | ||
==Potent Vitamin D Receptor Agonist== | ==Potent Vitamin D Receptor Agonist== | ||
<StructureSection load='5e7v' size='340' side='right' caption='[[5e7v]], [[Resolution|resolution]] 2.40Å' scene=''> | <StructureSection load='5e7v' size='340' side='right'caption='[[5e7v]], [[Resolution|resolution]] 2.40Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5e7v]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5E7V OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[5e7v]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Danio_rerio Danio rerio] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5E7V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5E7V FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=M7E:1-ALPHA-HYDROXY-27-NOR-25-O-CARBONYL-VITAMIN+D3'>M7E</scene></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=M7E:1-ALPHA-HYDROXY-27-NOR-25-O-CARBONYL-VITAMIN+D3'>M7E</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5e7v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5e7v OCA], [https://pdbe.org/5e7v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5e7v RCSB], [https://www.ebi.ac.uk/pdbsum/5e7v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5e7v ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/VDRA_DANRE VDRA_DANRE] Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Regulates transcription of hormone sensitive genes via its association with the WINAC complex, a chromatin-remodeling complex. Plays a central role in calcium homeostasis.<ref>PMID:17218092</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 20: | Line 21: | ||
==See Also== | ==See Also== | ||
*[[Vitamin D receptor|Vitamin D receptor]] | *[[Vitamin D receptor 3D structures|Vitamin D receptor 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Danio rerio]] | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Belorusova AY]] | ||
[[Category: | [[Category: Maestro MA]] | ||
[[Category: | [[Category: Mourino A]] | ||
[[Category: | [[Category: Otero R]] | ||
[[Category: | [[Category: Perez-Fernandez R]] | ||
[[Category: | [[Category: Rochel N]] | ||
[[Category: | [[Category: Seoane S]] | ||
[[Category: | [[Category: Sigueiro R]] | ||