5e7s: Difference between revisions

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==Hexameric structure of a LonA protease domain in active state==
==Hexameric structure of a LonA protease domain in active state==
<StructureSection load='5e7s' size='340' side='right' caption='[[5e7s]], [[Resolution|resolution]] 3.03&Aring;' scene=''>
<StructureSection load='5e7s' size='340' side='right'caption='[[5e7s]], [[Resolution|resolution]] 3.03&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5e7s]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_baa-399 Atcc baa-399]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5E7S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5E7S FirstGlance]. <br>
<table><tr><td colspan='2'>[[5e7s]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Meiothermus_taiwanensis Meiothermus taiwanensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5E7S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5E7S FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">lonA1, lon ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=172827 ATCC BAA-399])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.03&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endopeptidase_La Endopeptidase La], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.53 3.4.21.53] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5e7s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5e7s OCA], [https://pdbe.org/5e7s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5e7s RCSB], [https://www.ebi.ac.uk/pdbsum/5e7s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5e7s ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5e7s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5e7s OCA], [http://pdbe.org/5e7s PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5e7s RCSB], [http://www.ebi.ac.uk/pdbsum/5e7s PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5e7s ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/A0A059VAZ3_9DEIN A0A059VAZ3_9DEIN]] ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.[HAMAP-Rule:MF_01973]  
[https://www.uniprot.org/uniprot/A0A059VAZ3_9DEIN A0A059VAZ3_9DEIN] ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.[HAMAP-Rule:MF_01973]
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Atcc baa-399]]
[[Category: Large Structures]]
[[Category: Endopeptidase La]]
[[Category: Meiothermus taiwanensis]]
[[Category: Chang, C I]]
[[Category: Chang C-I]]
[[Category: Lin, C C]]
[[Category: Lin C-C]]
[[Category: Su, S C]]
[[Category: Su S-C]]
[[Category: Aaa+ domain]]
[[Category: Hydrolase]]
[[Category: Lon protease]]
[[Category: Protease domain]]

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