1tch: Difference between revisions

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OCA

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 ==STRUCTURE-ACTIVITY RELATIONSHIPS OF MU-CONOTOXIN GIIIA: STRUCTURE DETERMINATION OF ACTIVE AND INACTIVE SODIUM CHANNEL BLOCKER PEPTIDES BY NMR AND SIMULATED ANNEALING CALCULATIONS==
-<StructureSection load='1tch' size='340' side='right'caption='[[1tch]], [[NMR_Ensembles_of_Models | 1 NMR models]]' scene=''>
+<StructureSection load='1tch' size='340' side='right'caption='[[1tch]]' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1tch]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TCH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1TCH FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1tch]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TCH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TCH FirstGlance]. <br>
-</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=HYP:4-HYDROXYPROLINE'>HYP</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1tck|1tck]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HYP:4-HYDROXYPROLINE'>HYP</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1tch FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tch OCA], [http://pdbe.org/1tch PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1tch RCSB], [http://www.ebi.ac.uk/pdbsum/1tch PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1tch ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tch FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tch OCA], [https://pdbe.org/1tch PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tch RCSB], [https://www.ebi.ac.uk/pdbsum/1tch PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tch ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/CM3A_CONGE CM3A_CONGE]] Mu-conotoxins block voltage-gated sodium channels (Nav). This toxin potently blocks Nav1.4/SCN4A. It also moderately blocks rNav1.1/SCN1A, rNav1.2/SCN2A, and mNav1.6/SCN8A. The inhibition is reversible. Induces paralysis in vertebrates.<ref>PMID:18950653</ref> <ref>PMID:21652775</ref> <ref>PMID:2410412</ref>
+[https://www.uniprot.org/uniprot/CM3A_CONGE CM3A_CONGE] Mu-conotoxins block voltage-gated sodium channels (Nav). This toxin potently blocks Nav1.4/SCN4A. It also moderately blocks rNav1.1/SCN1A, rNav1.2/SCN2A, and mNav1.6/SCN8A. The inhibition is reversible. Induces paralysis in vertebrates.<ref>PMID:18950653</ref> <ref>PMID:21652775</ref> <ref>PMID:2410412</ref>
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 24: / Line 24: @@
 </StructureSection>
 [[Category: Large Structures]]
-[[Category: Inagaki, F]]
+[[Category: Inagaki F]]
-[[Category: Kohda, D]]
+[[Category: Kohda D]]
-[[Category: Lancelin, J M]]
+[[Category: Lancelin J-M]]
-[[Category: Neurotoxin]]