5d08: Difference between revisions

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==Crystal structure of selenomethionine-labeled epoxyqueuosine reductase==
==Crystal structure of selenomethionine-labeled epoxyqueuosine reductase==
<StructureSection load='5d08' size='340' side='right' caption='[[5d08]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
<StructureSection load='5d08' size='340' side='right'caption='[[5d08]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5d08]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacsu Bacsu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5D08 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5D08 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5d08]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis_subsp._subtilis_str._168 Bacillus subtilis subsp. subtilis str. 168]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5D08 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5D08 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=B12:COBALAMIN'>B12</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=B12:COBALAMIN'>B12</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5d08 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5d08 OCA], [https://pdbe.org/5d08 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5d08 RCSB], [https://www.ebi.ac.uk/pdbsum/5d08 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5d08 ProSAT]</span></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5d0a|5d0a]], [[5d0b|5d0b]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">queG, ygaP, yhbA, BSU08910 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224308 BACSU])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Epoxyqueuosine_reductase Epoxyqueuosine reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.17.99.6 1.17.99.6] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5d08 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5d08 OCA], [http://pdbe.org/5d08 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5d08 RCSB], [http://www.ebi.ac.uk/pdbsum/5d08 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5d08 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/QUEG_BACSU QUEG_BACSU]] Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).[HAMAP-Rule:MF_00916]<ref>PMID:21502530</ref>
[https://www.uniprot.org/uniprot/QUEG_BACSU QUEG_BACSU] Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).[HAMAP-Rule:MF_00916]<ref>PMID:21502530</ref>  
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<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacsu]]
[[Category: Bacillus subtilis subsp. subtilis str. 168]]
[[Category: Epoxyqueuosine reductase]]
[[Category: Large Structures]]
[[Category: Bandarian, V]]
[[Category: Bandarian V]]
[[Category: Dowling, D P]]
[[Category: Dowling DP]]
[[Category: Drennan, C L]]
[[Category: Drennan CL]]
[[Category: Kohrer, C]]
[[Category: Kohrer C]]
[[Category: Miles, Z D]]
[[Category: Miles ZD]]
[[Category: B12]]
[[Category: Heat-domain]]
[[Category: Oxidoreductase]]
[[Category: Queuosine]]
[[Category: Trna modification]]

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