Lysine-specific histone demethylase 3D structures: Difference between revisions

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**[[2com]], [[2l3d]] - hLSD1 SWIRM domain 174-273 – human – NMR<br />
**[[2com]], [[2l3d]] - hLSD1 SWIRM domain 174-273 – human – NMR<br />
**[[5it3]], [[6e1f]] - hLSD1 SWIRM domain<br />
**[[5it3]], [[6e1f]] - hLSD1 SWIRM domain<br />
**[[2h94]], [[2dw4]], [[2z3y]], [[2z5u]], [[4fwe]], [[4fwj]], [[4gu1]] – hLSD1 170-833<br />
**[[2h94]], [[2dw4]], [[2z3y]], [[2z5u]], [[4fwe]], [[4fwj]], [[4gu1]], [[6nqm]] – hLSD1 170-833<br />
**[[2hko]] – hLSD1 (mutant)<br />
**[[2hko]] – hLSD1 (mutant)<br />
**[[2ejr]], [[3abt]], [[3abu]] – hLSD1 + tranylcypromine derivative<br />
**[[2ejr]], [[3abt]], [[3abu]] – hLSD1 + tranylcypromine derivative<br />
**[[4gut]], [[4guu]] – hLSD1 + oxidoreductase<br />
**[[4gut]], [[4guu]] – hLSD1 + oxidoreductase<br />
**[[6nqu]], [[6kgo]], [[6kgp]], [[6kgq]], [[6kgr]] – hLSD1 + inhibitor<br />
**[[6nqu]], [[6kgo]], [[6kgp]], [[6kgq]], [[6kgr]], [[7vqs]], [[7vqt]], [[7vqu]], [[7w3l]] – hLSD1 + inhibitor<br />
**[[6nr5]] – hLSD1 + phenelzine sulfate<br />
**[[6nr5]] – hLSD1 + phenelzine sulfate<br />
**[[7xw8]] – hLSD1 + pteridine derivative<br />


*LSD1 complex with histone H3 peptide
*LSD1 complex with histone H3 peptide
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*LSD1 complex with CoREST
*LSD1 complex with CoREST


**[[4czz]] - hLSD1 + CoREST <br />
**[[5l3b]], [[5l3c]], [[5l3d]] - hLSD1 (mutant) + CoREST <br />
**[[7zry]] – hLSD1 + CoREST SANT1 and SANT2 domains 305-482<br />
**[[2iw5]], [[2uxn]], [[2uxx]] - hLSD1 SWIRM + amine oxidase domains + CoREST SANT1 and SANT2 domains<br />
**[[2iw5]], [[2uxn]], [[2uxx]] - hLSD1 SWIRM + amine oxidase domains + CoREST SANT1 and SANT2 domains<br />
**[[2v1d]], [[5x60]], [[5h6r]], [[5h6q]] - hLSD1 residues 123-852 + CoREST SANT1 and SANT2 domains + histone H3 residues 2-22 (mutant)<br />
**[[2v1d]], [[5x60]], [[5h6r]], [[5h6q]] - hLSD1 residues 123-852 + CoREST SANT1 and SANT2 domains + histone H3 residues 2-22 (mutant)<br />
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**[[4bay]] - hLSD1 residues 192-876 + CoREST residues 308-440 <br />
**[[4bay]] - hLSD1 residues 192-876 + CoREST residues 308-440 <br />
**[[4kum]] - hLSD1 SWIRM + FAD domains + CoREST residues 289-485 <br />
**[[4kum]] - hLSD1 SWIRM + FAD domains + CoREST residues 289-485 <br />
**[[4czz]], [[6kgk]] - hLSD1 + CoREST <br />
**[[6kgk]] - hLSD1 172-833 + CoREST <br />
**[[5l3b]], [[5l3c]], [[5l3d]],  - hLSD1 (mutant) + CoREST <br />
**[[4uv8]], [[4uv9]], [[4uva]], [[4uvb]], [[4uvc]] - hLSD1 + CoREST + irreversible inhibitor<br />
**[[4uv8]], [[4uv9]], [[4uva]], [[4uvb]], [[4uvc]] - hLSD1 + CoREST + irreversible inhibitor<br />
**[[5l3e]], [[5lbq]], [[5lgn]], [[5lgt]], [[5lgu]], [[5lhg]], [[5lhh]], [[5lhi]] - hLSD1 + CoREST + reversible inhibitor<br />
**[[5l3e]], [[5lbq]], [[5lgn]], [[5lgt]], [[5lgu]], [[5lhg]], [[5lhh]], [[5lhi]] - hLSD1 + CoREST + reversible inhibitor<br />
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**[[4guu]] – hLSD2 + NPAC + tranylcypromine <br />
**[[4guu]] – hLSD2 + NPAC + tranylcypromine <br />
**[[4gu0]] – hLSD2 + histone 3.3 peptide <br />
**[[4gu0]] – hLSD2 + histone 3.3 peptide <br />
**[[7xe1]], [[7xe2]], [[7xe3]] – hLSD2 + inhibitor <br />
**[[6r25]], [[6r1t]], [[6r1u]] – hLSD2 + NPAC + histones 3,4,2A,2B + DNA – Cryo EM <br />
**[[6r25]], [[6r1t]], [[6r1u]] – hLSD2 + NPAC + histones 3,4,2A,2B + DNA – Cryo EM <br />


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**[[6g8f]], [[6fuk]], [[6ful]], [[6ete]] – hKDM6A + inhibitor<br />
**[[6g8f]], [[6fuk]], [[6ful]], [[6ete]] – hKDM6A + inhibitor<br />
**[[3avr]], [[3avs]] – hKDM6A 880-1401 + H3 peptide + oxalylglycine<br />


*lysine-specific histone demethylase Ref6 see [[Jumonji domain-containing protein 3D structures]]  
*lysine-specific histone demethylase Ref6 see [[Jumonji domain-containing protein 3D structures]]  

Latest revision as of 10:26, 19 June 2023

3D structures of lysine-specific histone demethylase3D structures of lysine-specific histone demethylase

Updated on 19-June-2023

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Michal Harel