Lysin: Difference between revisions

Latest revision as of 13:34, 18 June 2023

Function

Lysin (Lys) is a protein which cleaves cell walls. Egg Lysin, a protein from abalone sperm, creates a hole in the envelope of the egg, permitting the sperm to pass through the envelope and fuse with the egg.

Structural highlights

The structure of lysin, refined at 1.9 angstroms resolution, reveals an alpha-helical, amphipathic molecule. . you can see the alpha helixes in pink. exhibits three features: two tracks of basic residues that span the length of the molecule, a solvent-exposed cluster of ,(in green) and an extended amino-terminal hypervariable domain that is species-specific. The structure suggests possible mechanisms of action^[1].

3D structure of lysin

Lysin 3D structures

ReferencesReferences

↑ Shaw A, McRee DE, Vacquier VD, Stout CD. The crystal structure of lysin, a fertilization protein. Science. 1993 Dec 17;262(5141):1864-7. PMID:8266073

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Carmit Ginesin, Michal Harel, Jaime Prilusky, Alexander Berchansky, Joel L. Sussman

[1] Shaw A, McRee DE, Vacquier VD, Stout CD. The crystal structure of lysin, a fertilization protein. Science. 1993 Dec 17;262(5141):1864-7. PMID:8266073

[1]

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-==MazE nisayon (maybe something like 'Structure')==
+<StructureSection load='' size='340' side='right' caption='Abalone lysin (PDB code [[1lis]])' scene='60/607850/Lysin_fertilization_protein/1'>
-<StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''>
-This is a default text for your page '''Carmit Gineisn/Test page'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.
-You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.
 == Function ==
-== Disease ==
+'''Lysin''' (Lys) is a protein which cleaves cell walls.  Egg  Lysin, a protein from abalone sperm, creates a hole in the envelope of the egg, permitting the sperm to pass through the envelope and fuse with the egg.
-== Relevance ==
+== Structural highlights ==
+The structure of lysin, refined at 1.9 angstroms resolution, reveals an alpha-helical, amphipathic molecule. <scene name='60/607850/Alpha_helixes/1'>To see alpha helixes press here</scene>. you can see the alpha helixes in pink. <scene name='60/607850/Surface/1'>the surface of the protein</scene> exhibits three features: two tracks of basic residues that span the length of the molecule, a solvent-exposed cluster of <scene name='60/607850/Aromatic_and_aliphatic/1'>aromatic and aliphatic amino acids</scene>,(in green) and an extended amino-terminal hypervariable domain that is species-specific. The structure suggests possible mechanisms of action<ref>PMID:8266073</ref>.
-== Structural highlights ==
+== 3D structure of lysin ==
-<scene name='60/607850/Mazef_complex/1'>TextToBeDisplayed</scene> explanation
-This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
+[[Lysin 3D structures]]
 </StructureSection>
 == References ==
 <references/>
+[[Category:Topic Page]]