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==HUMAN MED26 N-TERMINAL DOMAIN (1-92)== | ==HUMAN MED26 N-TERMINAL DOMAIN (1-92)== | ||
<StructureSection load='5odd' size='340' side='right' caption='[[5odd | <StructureSection load='5odd' size='340' side='right'caption='[[5odd]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5odd]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[5odd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2mzo 2mzo]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ODD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ODD FirstGlance]. <br> | ||
</td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5odd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5odd OCA], [https://pdbe.org/5odd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5odd RCSB], [https://www.ebi.ac.uk/pdbsum/5odd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5odd ProSAT]</span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/MED26_HUMAN MED26_HUMAN] Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</div> | </div> | ||
<div class="pdbe-citations 5odd" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5odd" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Mediator|Mediator]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Cantrelle | [[Category: Large Structures]] | ||
[[Category: Dewitte | [[Category: Cantrelle F-X]] | ||
[[Category: Hanoulle | [[Category: Dewitte F]] | ||
[[Category: Landrieu | [[Category: Hanoulle X]] | ||
[[Category: Lens | [[Category: Landrieu I]] | ||
[[Category: Perruzini | [[Category: Lens Z]] | ||
[[Category: Verger | [[Category: Perruzini R]] | ||
[[Category: Villeret | [[Category: Verger A]] | ||
[[Category: Villeret V]] | |||