5az5: Difference between revisions

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 ==Crystal structure of human TLR8 in complex with MB-343==
-<StructureSection load='5az5' size='340' side='right' caption='[[5az5]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
+<StructureSection load='5az5' size='340' side='right'caption='[[5az5]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[5az5]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AZ5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5AZ5 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[5az5]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AZ5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5AZ5 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=MBL:1-PENTYL-4-PHENYL-IMIDAZOL-2-AMINE'>MBL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=MBL:1-PENTYL-4-PHENYL-IMIDAZOL-2-AMINE'>MBL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5az5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5az5 OCA], [http://pdbe.org/5az5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5az5 RCSB], [http://www.ebi.ac.uk/pdbsum/5az5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5az5 ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5az5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5az5 OCA], [https://pdbe.org/5az5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5az5 RCSB], [https://www.ebi.ac.uk/pdbsum/5az5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5az5 ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/TLR8_HUMAN TLR8_HUMAN]] Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.<ref>PMID:17932028</ref>
+[https://www.uniprot.org/uniprot/TLR8_HUMAN TLR8_HUMAN] Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.<ref>PMID:17932028</ref>
+==See Also==
+*[[Toll-like Receptor 3D structures|Toll-like Receptor 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Ohto, U]]
+[[Category: Homo sapiens]]
-[[Category: Shimizu, T]]
+[[Category: Large Structures]]
-[[Category: Tanji, H]]
+[[Category: Ohto U]]
-[[Category: Adjuvant]]
+[[Category: Shimizu T]]
-[[Category: Glycosylation]]
+[[Category: Tanji H]]
-[[Category: Immune system]]
-[[Category: Innate immunity]]
-[[Category: Tlr]]
-[[Category: Tlr8]]
-[[Category: Vaccine adjuvant]]
-[[Category: Viral infection]]