Inosine monophosphate dehydrogenase 3D structures

3D structures of inosine monophosphate dehydrogenase3D structures of inosine monophosphate dehydrogenase

Updated on 29-May-2023

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• IMPDH
  • 1ak5 – TfIMPDH – Tritrichomonas foetus
    
  • 1eep – IMPDH – Borellia burgdorferi
    
  • 1zfj – IMPDH catalytic domain – Streptococcus pyogenes
    
  • 7xlo – IMPDH catalytic domain 1-97, 208-496 – Methanocaldococcus jannaschii
    
  • 1vrd – IMPDH – Thermotoga maritima
    
  • 3ffs – CpIMPDH – Cryptosporidium parvum
    
  • 3r2g – IMPDH – Legionella pneumophila
    
  • 3tsb, 4mjm, 4myx – BaIMPDH (mutant) – Bacillus anthracis
    
  • 4fez – VcIMPDH – Vibrio cholerae
    
  • 4avf, 3zfh, 6gjv – PaIMPDH – Pseudomonas aeruginosa
    
  • 5ahl – PaIMPDH (mutant)
    
  • 4xwu – AgIMPDH (mutant) – Ashbya gossypii
    
  • 6kcf – IMPDH – Liberibacter asiaticus
    
• IMPDH binary complex
  • 1jcn – hMPDH 1 + IMP derivative - human
    
  • 6udp – hMPDH 2 + IMP – Cryo EM
    
  • 1jr1 – hMPDH 2 + mycophenolic acid
    
  • 6i0m – hMPDH 2 + GDP
    
  • 6i0o – hMPDH 2 + GTP
    
  • 1me8 – TfIMPDH + ribavirin monophosphate
    
  • 1pvn – TfIMPDH catalytic domain + transition state analog
    
  • 1me9 – TfIMPDH + IMP
    
  • 2cu0 – IMPDH + xanthosine monophosphate – Pyrococcus horikoshii
    
  • 5upx – LmIMPDH + xanthosine monophosphate – Listeria monocytogenes
    
  • 8ebc – LmIMPDH + IMP
    
  • 3usb – BaIMPDH + IMP
    
  • 6mgu – BaIMPDH + oxaosine monophosphate
    
  • 3tsd – BaIMPDH (mutant) + xanthosine monophosphate
    
  • 4ix2 – VcIMPDH + IMP
    
  • 4qq3 – VcIMPDH (mutant) + XMP
    
  • 4dqw – PaIMPDH + ATP
    
  • 6gk9 – PaIMPDH + inhibitor
    
  • 5ahm, 5ahn – PaIMPDH (mutant) + IMP
    
  • 6mgr – CjIMPDH catalytic domain + oxanosin monophosphate – Campylobacter jejuni
    
  • 4r7j – CjIMPDH catalytic domain (mutant) + IMP
    
  • 5uqh, 5uqf, 5uqg – CjIMPDH catalytic domain (mutant) + inhibitor
    
  • 4xtd, 4xti – AgIMPDH (mutant) + IMP
    
  • 4z0g – AgIMPDH (mutant) + GMP
    
  • 5mcp – AgIMPDH + ATP
    
  • 6d4q, 6d4r, 6d4s, 6d4t, 6d4u, 6d4v, 6d4w, 6mjy – IMPDH + inhibitor – Mycobacterium thermoresistibile
    
  • 6lk4 – TbIMPDH + GTP – Trypanosoma brucei
    
• IMPDH ternary complex with inosinic acid (IMP) and inhibitor
  • 1b3o – hMPDH 2 + selenazole inhibitor + IMP derivative
    
  • 4ixh, 3khj, 4qj1 – CpIMPDH catalytic domain + inhibitor + IMP
    
  • 4rv8 – CpMPDH (mutant) + IMP + inhibitor
    
  • 4zqn, 4zqo, 4zqp, 4zqr, 5upu, 5ou1, 5ou2, 5ou3 - MtIMPDH catalytic domain + inhibitor + IMP
    
  • 5upv - MtIMPDH catalytic domain (mutant) + inhibitor + IMP
    
  • 5j5r, 5k4x, 5k4z - MrIMPDH + inhibitor + IMP – Mycobacterium thermoresistibile
    
  • 7mtx, 5urs, 5uuv, 7mtu, 5uuz, 7mtu, 7mtx – BaIMPDH catalytic domain + inhibitor + IMP
    
  • 4my1, 4mya, 4my8, 4my9, 4qm1 – BaIMPDH catalytic domain (mutant) + inhibitor + IMP
    
  • 4mz1, 4mz8 – CjIMPDH catalytic domain (mutant) + inhibitor + IMP
    
  • 5urq – CjIMPDH catalytic domain + inhibitor + IMP
    
  • 4q32, 4q33 – ClpMPDH + IMP + inhibitor – Clostridium perfringens
    
  • 5uwx]], 5uxe, 5uzc, 5uze, 5uzs, 5vsv – ClpMPDH (mutant) + IMP + inhibitor
    
  • 4af0 – IMPDH + mycophenolic acid + IMP – Cryptococcus neoformans
    
  • 5upy - LmIMPDH catalytic domain + inhibitor + IMP
    
• IMPDH other ternary complexes
  • 6u8e, 6u8s, 6ua5 – hMPDH 2 + NAD + IMP – Cryo EM
    
  • 6u8n, 6u8r – hMPDH 2 + NAD + ATP + IMP – Cryo EM
    
  • 6uc2 – hMPDH 2 + ATP + GTP – Cryo EM
    
  • 6udo, 6udq – hMPDH 2 + ATP + GTP + IMP – Cryo EM
    
  • 6u9o, 6ua2, 6ua4, 6uaj – hMPDH 2 + NAD + ATP + GTP + IMP – Cryo EM
    
  • 1nfb – hMPDH 2 + NAD + IMP derivative
    
  • 1nf7 – hMPDH 2 + mycophenolic adenine dinucleotide + ribavirin monophosphate
    
  • 1me7 – TfIMPDH + ribavirin monophosphate + mycophenolic acid
    
  • 1lrt – TfIMPDH + adenine derivative + IMP
    
  • 1meh – TfIMPDH + mycophenolic acid + IMP
    
  • 1mei – TfIMPDH + mycophenolic acid + xanthosine monophosphate
    
  • 1mew – TfIMPDH + NAD + xanthosine monophosphate
    
  • 4zqm – MtIMPDH + NAD + xanthosine monophosphate – Mycobacterium tuberculosis
    
  • 4fo4, 4fxs – VcIMPDH + mycophenolic acid + IMP
    
  • 4qne – VcIMPDH (mutant) + NAD + IMP
    
  • 4x3z – VcIMPDH (mutant) + NAD + XMP
    
  • 4z87 – AgIMPDH + GDP + GMP
    
  • 5tc3 – AgIMPDH + ATP + GDP
    
  • 6rpu – AgIMPDH + AP5G + GDP
    
  • 6rfu – TbIMPDH + ATP + GMP