1acx: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
| (5 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
==ACTINOXANTHIN STRUCTURE AT THE ATOMIC LEVEL (RUSSIAN)== | ==ACTINOXANTHIN STRUCTURE AT THE ATOMIC LEVEL (RUSSIAN)== | ||
<StructureSection load='1acx' size='340' side='right' caption='[[1acx]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='1acx' size='340' side='right'caption='[[1acx]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1acx]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[1acx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_globisporus Streptomyces globisporus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ACX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ACX FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1acx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1acx OCA], [https://pdbe.org/1acx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1acx RCSB], [https://www.ebi.ac.uk/pdbsum/1acx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1acx ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/ATXA_STRGL ATXA_STRGL] Binds non-covalently to a chromophore which is the cytotoxic and mutagenic component of the antibiotic. The chromophore binds to DNA as a weak intercalator and causes single- and double-strand breaks. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: Streptomyces globisporus]] | [[Category: Streptomyces globisporus]] | ||
[[Category: Kuzin | [[Category: Kuzin AP]] | ||
[[Category: Pletnev | [[Category: Pletnev VZ]] | ||
Latest revision as of 12:53, 19 April 2023
ACTINOXANTHIN STRUCTURE AT THE ATOMIC LEVEL (RUSSIAN)ACTINOXANTHIN STRUCTURE AT THE ATOMIC LEVEL (RUSSIAN)
Structural highlights
FunctionATXA_STRGL Binds non-covalently to a chromophore which is the cytotoxic and mutagenic component of the antibiotic. The chromophore binds to DNA as a weak intercalator and causes single- and double-strand breaks. |
| ||||||||||||||