Flavin reductase: Difference between revisions
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<StructureSection load=' | <StructureSection load='' size='350' side='right' scene='49/490853/Cv/1' caption='Human flavin reductase complex with biliverdin IX α and NADP (PDB code [[1he2]]) '> | ||
== Function == | == Function == | ||
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== Structural insights == | == Structural insights == | ||
The <scene name='49/490853/Cv/ | The <scene name='49/490853/Cv/4'>NADP containing active site can accommodate a variety of ligands</scene> because the binding is achieved mainly via hydrophobic interactions ({{Template:ColorKey_Hydrophobic}}, {{Template:ColorKey_Polar}}).<ref>PMID:11224564</ref> | ||
</StructureSection> | </StructureSection> | ||
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
{{#tree:id=OrganizedByTopic|openlevels=0| | |||
*NADPH-dependent Flavin reductase or biliverdin IX beta reductase | |||
**[[1hdo]], [[7er6]] - hFR + NADP - human<br /> | |||
**[[6opl]] – hFR (mutant) + NADP <br /> | |||
**[[1he2]] - hFR + biliverdin IX α + NADP<BR /> | |||
**[[1he3]] - hFR + mesobiliverdin IV α + NADP<BR /> | |||
**[[1he4]] - hFR + FMN + NADP<BR /> | |||
**[[1he5]] - hFR + lumichrome + NADP<BR /> | |||
**[[5ooh]] – hFR + NADP + erythrosine<br /> | |||
**[[5oog]] – hFR + NADP + phloxine + cyanosine<br /> | |||
**[[7er7]], [[7er8]], [[7er9]], [[7era]], [[7erb]], [[7erc]], [[7erd]], [[7ere]] – hFR + NADP + drug<br /> | |||
**[[3pft]] - FR (mutant) + FMN – ''Mycobacterium goodii''<br /> | |||
**[[5cho]] - FR + FAD – uncultured bacteria<br /> | |||
**[[1qfj]] – FR – ''Escherichia coli''<br /> | |||
**[[1bkj]] – VhFR + FMN – ''Vibrio harveyi''<br /> | |||
**[[2bkj]] - VhFR + NAD + FMN<br /> | |||
*NADH-dependent Flavin reductase | |||
**[[1rz0]] – GtFR + FAD – ''Geobacillus thermoglucosidasius''<br /> | |||
**[[1rz1]] - GtFR + FAD + NAD<br /> | |||
**[[5n6q]] - PpFR + FMN – ''Pseudomonas putida''<br /> | |||
**[[4uth]] - PpFR (mutant) + FMN <br /> | |||
**[[5lnj]], [[5lni]], [[4uti]], [[4utj]] - PpFR (mutant) + FMN derivative + coumarin derivative<br /> | |||
**[[2d36]] - StFR + FMN – ''Sulfurisphaera tokodaii''<br /> | |||
**[[2d37]] - StFR + FMN + NAD<br /> | |||
**[[2d38]] - StFR + FMN + NADP<br /> | |||
}} | |||
== References == | == References == | ||
<references/> | <references/> |