Estrogen receptor 3D structures: Difference between revisions
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} - For a general description of the protein see [[Estrogen receptor]] | ||
{{#tree:id=OrganizedByTopic|openlevels=0| | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
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**[[2bj4]], [[2jf9]], [[2jfa]], [[1pcg]], [[5gtr]], [[5gs4]] - hERα LBD + peptide antagonist<br /> | **[[2bj4]], [[2jf9]], [[2jfa]], [[1pcg]], [[5gtr]], [[5gs4]] - hERα LBD + peptide antagonist<br /> | ||
**[[2q6j]], [[2p15]], [[3erd]], [[1l2i]] - hERα LBD + GRIP peptide<br /> | **[[2q6j]], [[2p15]], [[3erd]], [[1l2i]] - hERα LBD + GRIP peptide<br /> | ||
**[[6d0f]], [[6czn]] - hERα LBD (mutant) + GRIP peptide<br /> | **[[6d0f]], [[6cbz]], [[6czn]] - hERα LBD (mutant) + GRIP peptide<br /> | ||
**[[7rnm]] - hERα LBD + GRIP peptide + pyrimidine derivative<br /> | |||
**[[7rke]], [[7sfo]], [[7t2x]] - hERα LBD (mutant) + GRIP peptide + pyrimidine derivative<br /> | |||
**[[6cbz]], [[5wgq]], [[5wgd]] - hERα LBD (mutant) + GRIP peptide + EST<br /> | **[[6cbz]], [[5wgq]], [[5wgd]] - hERα LBD (mutant) + GRIP peptide + EST<br /> | ||
**[[6pit]] - hERα LBD (mutant) + stapled peptide + EST<br /> | **[[6pit]] - hERα LBD (mutant) + stapled peptide + EST<br /> | ||
**[[4q13]] - hERα LBD (mutant) + glucocorticoid receptor-interacting protein peptide<br /> | **[[4q13]] - hERα LBD (mutant) + glucocorticoid receptor-interacting protein peptide<br /> | ||
**[[ | **[[7ujo]] - hERα LBD + anti-hormone<br /> | ||
**[[ | **[[7uj7]] - hERα LBD (mutant) + anti-hormone<br /> | ||
**[[5krf]] - hERα LBD (mutant) + peptide + anti-hormone<br /> | **[[5krf]] - hERα LBD (mutant) + peptide + anti-hormone<br /> | ||
**[[2yat]] - hERα LBD (mutant) + EST derivative<br /> | **[[2yat]] - hERα LBD (mutant) + EST derivative<br /> | ||
**[[6iar]], [[6dfn]], [[6df6]] - hERα LBD + antagonist<br /> | **[[6iar]], [[6dfn]], [[6df6]], [[6zoq]], [[6zor]], [[6zos]], [[7msa], [[7r62]], [[7qvj]], [[7qvl]], [[7te7]], [[8du8]], [[8duc]], [[8dud]] [[8dui]] - hERα LBD + antagonist<br /> | ||
**[[5fqp]], [[5fqr]], [[5fqs]], [[5fqt]], [[5fqv]], [[5aau]], [[5aav]], [[5acc]], [[5ak2]], [[5di7]], [[5did]], [[5die]], [[5dig]], [[5dk9]], [[5dkb]], [[5dke]], [[5dkg]], [[5dks]], [[5dl4]], [[5dlr]], [[5dmc]], [[5dmf]], [[5dp0]], [[6chz]], [[6chw]], [[6c42]], [[6b0f]], [[5w9d]], [[5ufx]], [[5ufw]] - hERα LBD (mutant) + antagonist<br /> | **[[5fqp]], [[5fqr]], [[5fqs]], [[5fqt]], [[5fqv]], [[5aau]], [[5aav]], [[5acc]], [[5ak2]], [[5di7]], [[5did]], [[5die]], [[5dig]], [[5dk9]], [[5dkb]], [[5dke]], [[5dkg]], [[5dks]], [[5dl4]], [[5dlr]], [[5dmc]], [[5dmf]], [[5dp0]], [[6chz]], [[6chw]], [[6c42]], [[6b0f]], [[5w9d]], [[5ufx]], [[5ufw]], [[7n9o]], [[7rrx]], [[7rry]], [[7rrz]], [[7rs0]], [[7rs1]], [[7rs2]], [[7rs3]], [[7rs4]], [[7rs7]], [[7rs8]],[[7rs9]], [[7wnv]], [[8du6]], [[8du9]], [[8dub]], [[8dug]], [[8duh]], [[8dus]], [[8dv5]], [[8dv7]], [[8dv8]], [[8dvb]], [[7ndo]], [[7uj8]], [[8ev1]], [[8ev2]] - hERα LBD (mutant) + antagonist<br /> | ||
**[[6owc]] - hERα LBD (mutant) + pyridine derivative<br /> | **[[6owc]] - hERα LBD (mutant) + pyridine derivative<br /> | ||
**[[4q50]], [[5w9c]], [[6v87]] - hERα LBD (mutant) + tamoxifen derivative<br /> | **[[4q50]], [[5w9c]], [[6v87]] - hERα LBD (mutant) + tamoxifen derivative<br /> | ||
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**[[6pet]] - hERα LBD + hydroxychromene<br /> | **[[6pet]] - hERα LBD + hydroxychromene<br /> | ||
**[[6pfm]] - hERα LBD (mutant) + hydroxychromene<br /> | **[[6pfm]] - hERα LBD (mutant) + hydroxychromene<br /> | ||
**[[6psj]] - hERα LBD (mutant) + osteoporosis drug<br /> | **[[6psj]], [[6vgh]], [[7ujy]], [7ujw]], [[7ujc]], [[7ujm]], [[7kbs]] - hERα LBD (mutant) + osteoporosis drug<br /> | ||
**[[6wok]] - hERα LBD + breast cancer drug<br /> | **[[6wok]] - hERα LBD + breast cancer drug<br /> | ||
**[[6suo]] - hERα LBD + indole derivative<br /> | **[[6suo]] - hERα LBD + indole derivative<br /> | ||
**[[6sq0]] - hERα LBD (mutant) + indole derivative<br /> | **[[6sq0]] - hERα LBD (mutant) + indole derivative<br /> | ||
**[[6v8t]] - hERα LBD (mutant) + benzothiophene derivative<br /> | **[[6v8t]] - hERα LBD (mutant) + benzothiophene derivative<br /> | ||
**[[6vjd]], [[ | **[[6vjd]], [[7ujf]], [[6vpf]], [[7ujy]], [[7ujw]] - hERα LBD + modulator<br /> | ||
**[[6vgh]] - hERα LBD (mutant) + modulator<br /> | **[[6vgh]] - hERα LBD (mutant) + modulator<br /> | ||
**[[5t1z]] - hERα LBD + LXXLL motif (mutant) + ethoxy triphenylethylene<br /> | **[[5t1z]] - hERα LBD + LXXLL motif (mutant) + ethoxy triphenylethylene<br /> | ||
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**[[2ocf]] - hERα LBD (mutant) + fibronectin domain 10 + EST<br /> | **[[2ocf]] - hERα LBD (mutant) + fibronectin domain 10 + EST<br /> | ||
**[[2yja]] - hERα LBD + NCAO2 peptide<br /> | **[[2yja]] - hERα LBD + NCAO2 peptide<br /> | ||
**[[2b23]] - hERα LBD (mutant) + NCAO2 peptide<br /> | **[[2b23]], [[8ev1]], [[8ev2]] - hERα LBD (mutant) + NCAO2 peptide<br /> | ||
**[[4n1y]] - ERα LBD – pacific oyster<br /> | **[[4n1y]] - ERα LBD – pacific oyster<br /> | ||
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**[[5kri]], [[5krj]], [[5krk]], [[5krl]], [[5krm]], [[5kro]] - hERα LBD (mutant) + NCAO2 peptide + anti-hormone<br /> | **[[5kri]], [[5krj]], [[5krk]], [[5krl]], [[5krm]], [[5kro]] - hERα LBD (mutant) + NCAO2 peptide + anti-hormone<br /> | ||
**[[5egv]], [[ehj]], [[5ei1]], [[5eit]], [[5dxk]], [[5dxe]], [[5dxg]], [[5kro]] - hERα LBD (mutant) + NCAO2 peptide + anti-hormone<br /> | **[[5egv]], [[ehj]], [[5ei1]], [[5eit]], [[5dxk]], [[5dxe]], [[5dxg]], [[5kro]] - hERα LBD (mutant) + NCAO2 peptide + anti-hormone<br /> | ||
**[[7jhd]] - hERα LBD + NCAO2 peptide + antagonist<br /> | |||
**[[5dxe]], [[5dxg]], [[5dxk]], [[5dxm]], [[5dxp]], [[5dxq]], [[5dxr]], [[5dy8]], [[5dyb]], [[5dyd]], [[5dz0]], [[5dz1]], [[5dz3]], [[5dzh]], [[5dzi]], [[5e0w]], [[5e0x]], [[5e14]], [[5e15]], [[5e19]], [[5e1c]], [[5drj]], [[5drm]], [[5dtv]], [[5du5]], [[5due]], [[5dug]], [[5duh]], [[5dvs]], [[5dvv]], [[5dwe]], [[5dwg]], [[5dwi]], [[5dwj]], [[4iu7]], [[4iui]], [[4iv2]], [[4iv4]], [[4ivw]], [[4ivy]], [[4iw6]], [[4iw8]], [[4iwc]], [[4iwf]], [[5u2d]], [[5tld]], [[5tlf]], [[5tlg]], [[5tll]], [[5tlm]], [[5tlo]], [[5tlp]], [[5tlt]], [[5tlu]], [[5tlv]], [[5tlx]], [[5tly]], [[5tm1]], [[5tm2]], [[5tm3]], [[5tm4]], [[5tm5]], [[5tm6]], [[5tm7]], [[5tm8]], [[5tm9]], [[5tml]], [[5tmo]], [[5tmm]], [[5tmq]], [[5tmr]], [[5tms]], [[5tmt]], [[5tmu]], [[5tmv]], [[5tmw]], [[5tmz]], [[5tn1]], [[5tn3]], [[5tn4]], [[5tn5]], [[5tn6]], [[5tn7]], [[5tn8]], [[5ehj]] - hERα LBD (mutant) + NCAO2 peptide + antagonist<br /> | **[[5dxe]], [[5dxg]], [[5dxk]], [[5dxm]], [[5dxp]], [[5dxq]], [[5dxr]], [[5dy8]], [[5dyb]], [[5dyd]], [[5dz0]], [[5dz1]], [[5dz3]], [[5dzh]], [[5dzi]], [[5e0w]], [[5e0x]], [[5e14]], [[5e15]], [[5e19]], [[5e1c]], [[5drj]], [[5drm]], [[5dtv]], [[5du5]], [[5due]], [[5dug]], [[5duh]], [[5dvs]], [[5dvv]], [[5dwe]], [[5dwg]], [[5dwi]], [[5dwj]], [[4iu7]], [[4iui]], [[4iv2]], [[4iv4]], [[4ivw]], [[4ivy]], [[4iw6]], [[4iw8]], [[4iwc]], [[4iwf]], [[5u2d]], [[5tld]], [[5tlf]], [[5tlg]], [[5tll]], [[5tlm]], [[5tlo]], [[5tlp]], [[5tlt]], [[5tlu]], [[5tlv]], [[5tlx]], [[5tly]], [[5tm1]], [[5tm2]], [[5tm3]], [[5tm4]], [[5tm5]], [[5tm6]], [[5tm7]], [[5tm8]], [[5tm9]], [[5tml]], [[5tmo]], [[5tmm]], [[5tmq]], [[5tmr]], [[5tms]], [[5tmt]], [[5tmu]], [[5tmv]], [[5tmw]], [[5tmz]], [[5tn1]], [[5tn3]], [[5tn4]], [[5tn5]], [[5tn6]], [[5tn7]], [[5tn8]], [[5ehj]] - hERα LBD (mutant) + NCAO2 peptide + antagonist<br /> | ||
**[[5kcf]], [[5kct]], [[5kcu]], [[5kcw]], [[5kd9]], [[5kcc]], [[5kcd]], [[5kce]], [[4zn9]], [[4znh]], [[4zns]], [[4znt]], [[4znu]], [[4znv]], [[4znw]] - hERα LBD (mutant) + NCAO2 peptide + OBHS derivative<br /> | **[[5kcf]], [[5kct]], [[5kcu]], [[5kcw]], [[5kd9]], [[5kcc]], [[5kcd]], [[5kce]], [[4zn9]], [[4znh]], [[4zns]], [[4znt]], [[4znu]], [[4znv]], [[4znw]] - hERα LBD (mutant) + NCAO2 peptide + OBHS derivative<br /> | ||
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**[[1gwq]], [[2fai]], [[2g44]], [[2qzo]] - hERα LBD + NCAO2 peptide + ligand<br /> | **[[1gwq]], [[2fai]], [[2g44]], [[2qzo]] - hERα LBD + NCAO2 peptide + ligand<br /> | ||
**[[3l03]], [[3hm1]], [[3hlv]], [[1zky]], [[2b1v]], [[2b1z]], [[2qa6]], [[2qab]], [[2qgw]], [[2qh6]], [[2qr9]], [[2qse]], [[2qxm]] - hERα LBD (mutant) + NCAO2 peptide + ligand<br /> | **[[3l03]], [[3hm1]], [[3hlv]], [[1zky]], [[2b1v]], [[2b1z]], [[2qa6]], [[2qab]], [[2qgw]], [[2qh6]], [[2qr9]], [[2qse]], [[2qxm]] - hERα LBD (mutant) + NCAO2 peptide + ligand<br /> | ||
**[[2qa8]] - hERα LBD (mutant) + NCAO2 peptide + genistein<br /> | **[[2qa8]], [[7nfb]] - hERα LBD (mutant) + NCAO2 peptide + genistein<br /> | ||
**[[4pp6]], [[4ppp]], [[4pps]] - hERα LBD (mutant) + NCAO2 peptide + resveratrol derivative<br /> | **[[4pp6]], [[4ppp]], [[4pps]] - hERα LBD (mutant) + NCAO2 peptide + resveratrol derivative<br /> | ||
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**[[1x7e]] - hERα LBD + NCAO3 peptide + ligand<br /> | **[[1x7e]] - hERα LBD + NCAO3 peptide + ligand<br /> | ||
*Estrogen receptor α DNA binding domain | *Estrogen receptor α DNA binding domain 182-252 | ||
**[[1hcp]] – hERα DBD – NMR<br /> | **[[1hcp]] – hERα DBD – NMR<br /> | ||
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**[[6sbo]] – hERα residues 124-381 + pyrrolydin derivative<br /> | **[[6sbo]] – hERα residues 124-381 + pyrrolydin derivative<br /> | ||
*Estrogen receptor β ligand binding domain | *Estrogen receptor β ligand binding domain 261-500 | ||
**[[1qkm]] - hERβ LBD + genistein<br /> | **[[1qkm]] - hERβ LBD + genistein<br /> | ||
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**[[1u9e]] - hERβ LBD + NCAO peptide<br /> | **[[1u9e]] - hERβ LBD + NCAO peptide<br /> | ||
**[[1x76]], [[1x78]], [[1x7b]], [[1yy4]], [[1yye]], [[1zaf]], [[2j7y]], [[2nv7]], [[3omo]], [[3omp]], [[3omq]] - hERβ LBD + NCAO peptide + ligand<br /> | **[[1x76]], [[1x78]], [[1x7b]], [[1yy4]], [[1yye]], [[1zaf]], [[2j7y]], [[2nv7]], [[3omo]], [[3omp]], [[3omq]] - hERβ LBD + NCAO peptide + ligand<br /> | ||
**[[1x7j]] - hERβ LBD + NCAO peptide + genistein | **[[1x7j]] - hERβ LBD + NCAO peptide + genistein<br /> | ||
**[[7xvy]], [[7xvz]], [[7xwp]], [[7xwq]], [[7xwr]] - hERβ LBD (mutant) + NCAO1 peptide + DPN derivative<br /> | |||
**[[7nel]] - hERβ LBD (mutant) + NCAO2 peptide + estradiol<br /> | |||
}} | }} | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Latest revision as of 14:14, 23 February 2023
Updated on 23-February-2023 - For a general description of the protein see Estrogen receptor