Epoxide hydrolase 3D structures: Difference between revisions
Michal Harel (talk | contribs) New page: == 3D Structures of epoxide hydrolase== Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| *Epoxide hydrolase **[[2e... |
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*Epoxide hydrolase | *Epoxide hydrolase | ||
**[[ | **[[4qla]] – EH – silkworm<br /> | ||
**[[2cjp]] – pEH I – potato<br /> | **[[2cjp]] – pEH I – potato<br /> | ||
**[[3cxu]], [[4ufn]], [[4ufo]], [[4ufp]], [[4uhb]], [[4y9s]] – pEH (mutant) <br /> | **[[3cxu]], [[4ufn]], [[4ufo]], [[4ufp]], [[4uhb]], [[4y9s]] – pEH (mutant) <br /> | ||
**[[5xmd]] – mbEH – mung bean<br /> | **[[5xmd]] – mbEH – mung bean<br /> | ||
**[[5y6y]], [[5y5d]], [[5xm6]] – mbEH (mutant)<br /> | **[[5y6y]], [[5y5d]], [[5xm6]] – mbEH (mutant)<br /> | ||
**[[2e3j]] – MtEH B – ''Mycobacterium tuberculosis''<br /> | |||
**[[5cw2]] – EH A – ''Mycobacterium thermoresistibile<''br /> | |||
**[[1qo7]], [[3g02]] – AnEH (mutant) – ''Aspergillus niger''<br /> | |||
**[[6ix4]] – AuEH – ''Aspergillus usamii''<br /> | |||
**[[6ix2]] – AuSEH (mutant) <br /> | |||
**[[4i19]], [[4qa9]], [[5f4z]] – EH – ''Streptomyces carzinostaticus''<br /> | |||
**[[5cxo]], [[6unw]] – EH – ''Streptomyces albus''<br /> | |||
**[[5nfq]], [[5ng7]] – meEH – metagenome<br /> | |||
**[[7cg2]], [[7cg6]] – EH (mutant) – ''Vigna radiata''<br /> | |||
*Soluble epoxide hydrolase | *Soluble epoxide hydrolase or bifunctional epoxide hydrolase 2 | ||
**[[1s8o]], [[3i1y]], [[3i28]], [[3koo]], [[5ahx]], [[5fp0]] – hSEH – human<br /> | **[[1s8o]], [[3i1y]], [[3i28]], [[3koo]], [[5ahx]], [[5fp0]] – hSEH – human<br /> | ||
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**[[1ehy]] – SEH – ''Agrobacterium tumefaciens''<br /> | **[[1ehy]] – SEH – ''Agrobacterium tumefaciens''<br /> | ||
*Epoxide hydrolase complex with inhibitor | *Epoxide hydrolase complex with inhibitor; Domains: catalytic 222-555 | ||
**[[5yb5]] – mbEH (mutant) + styrene derivative<br /> | |||
**[[3g0i]] – AnEH + valpromide<br /> | **[[3g0i]] – AnEH + valpromide<br /> | ||
**[[3rga]] – SlEH + oxazolidinone inhibitor – ''Streptomyces lasaliensis''<br /> | **[[3rga]] – SlEH + oxazolidinone inhibitor – ''Streptomyces lasaliensis''<br /> | ||
**[[4rzm]] – SlEH + lasalocid A<br /> | **[[4rzm]] – SlEH + lasalocid A<br /> | ||
**[[ | **[[6n3k]] – TrSEH + urea derivative inhibitor – ''Trichoderma reesei''<br /> | ||
**[[6n3z]] – TrSEH + benzamide derivative inhibitor <br /> | |||
**[[6n5h]] – TrSEH + benzoate derivative inhibitor <br /> | |||
**[[6n5f]] – TrSEH + nonanamide derivative inhibitor <br /> | |||
**[[6n5g]] – TrSEH + piperidine derivative inhibitor<br /> | |||
**[[2zjf]] – MtSEH + inhibitor<br /> | |||
*Soluble epoxide hydrolase complex with inhibitor | *Soluble epoxide hydrolase complex with inhibitor | ||
**[[1vj5]], [[1zd2]], [[1zd3]], [[1zd4]], [[1zd5]], [[3wk4]], [[4c4x]], [[4c4y]], [[4c4z]], [[5ai5]], [[5akz]], [[5ali]], [[6aum]], [[6fr2 | **[[1vj5]], [[1zd2]], [[1zd3]], [[1zd4]], [[1zd5]], [[3wk4]], [[4c4x]], [[4c4y]], [[4c4z]], [[5ai5]], [[5akz]], [[5ali]], [[6aum]], [[6fr2]], [[6hgx]] – hSEH + urea derivative inhibitor<br /> | ||
**[[3otq]], [[3wk7]], [[4y2j]], [[4y2s]], [[4y2v]], [[5ak4]], [[5akh]], [[5aki]], [[5alk]], [[5alq]], [[5alv]], [[5aly]] – hSEH + pyrazole inhibitor<br /> | **[[3otq]], [[3wk7]], [[4y2j]], [[4y2s]], [[4y2v]], [[5ak4]], [[5akh]], [[5aki]], [[5alk]], [[5alq]], [[5alv]], [[5aly]] – hSEH + pyrazole inhibitor<br /> | ||
**[[5akj]], [[5alf]], [[5als]] – hSEH + imidazole inhibitor<br /> | **[[5akj]], [[5alf]], [[5als]] – hSEH + imidazole inhibitor<br /> | ||
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**[[3ans]], [[3ant]] – hSEH + synthetic inhibitor<br /> | **[[3ans]], [[3ant]] – hSEH + synthetic inhibitor<br /> | ||
**[[3pdc]], [[5ale]] – hSEH catalytic domain + benzoxazole inhibitor<br /> | **[[3pdc]], [[5ale]] – hSEH catalytic domain + benzoxazole inhibitor<br /> | ||
**[[4jnc]], [[5alx]] – hSEH catalytic domain + carboxamide inhibitor<br /> | **[[4jnc]], [[5alx]], [[7p4k]] – hSEH catalytic domain + carboxamide inhibitor<br /> | ||
**[[4x6x]], [[4x6y]] – hSEH catalytic domain + cyclopropane inhibitor<br /> | **[[4x6x]], [[4x6y]] – hSEH catalytic domain + cyclopropane inhibitor<br /> | ||
**[[7a7g]] – hSEH catalytic domain + inhibitor<br /> | |||
**[[4hai]], [[3wka]], [[4ocz]], [[4od0]], [[5ake]], [[5alh]], [[5am1]] – hSEH + piperidine derivative inhibitor<br /> | **[[4hai]], [[3wka]], [[4ocz]], [[4od0]], [[5ake]], [[5alh]], [[5am1]] – hSEH + piperidine derivative inhibitor<br /> | ||
**[[4y2p]], [[4y2q]], [[5ai4]], [[5ak5]], [[5ak6]], [[5alt]], [[5am5]] – hSEH + pyridine derivative inhibitor<br /> | **[[4y2p]], [[4y2q]], [[5ai4]], [[5ak5]], [[5ak6]], [[5alt]], [[5am5]] – hSEH + pyridine derivative inhibitor<br /> | ||
**[[4y2r]] – hSEH + piperazine derivative inhibitor<br /> | **[[4y2r]] – hSEH + piperazine derivative inhibitor<br /> | ||
**[[5akl]], [[5alm]], [[5am0]] – hSEH + pyrrolidine derivative inhibitor<br /> | **[[5akl]], [[5alm]], [[5am0]] – hSEH + pyrrolidine derivative inhibitor<br /> | ||
**[[6yl4]] – hSEH + benzamide derivative inhibitor <br /> | |||
**[[4y2t]], [[5aib]] – hSEH + benzyloxy derivative inhibitor<br /> | **[[4y2t]], [[5aib]] – hSEH + benzyloxy derivative inhibitor<br /> | ||
**[[3wkb]] – hSEH + quinoxaline derivative inhibitor<br /> | **[[3wkb]] – hSEH + quinoxaline derivative inhibitor<br /> | ||
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**[[3wke]], [[5am3]] – hSEH + carbamoyl derivative inhibitor<br /> | **[[3wke]], [[5am3]] – hSEH + carbamoyl derivative inhibitor<br /> | ||
**[[4j03]] – hSEH + fulvestrant<br /> | **[[4j03]] – hSEH + fulvestrant<br /> | ||
**[[6hgv]] – hSEH + talinonol<br /> | |||
**[[7eba]] – hSEH + kurarinone<br /> | |||
**[[5ai0]] – hSEH + phenyl oxadiazolamine inhibitor<br /> | **[[5ai0]] – hSEH + phenyl oxadiazolamine inhibitor<br /> | ||
**[[5ai9]] – hSEH + phenol derivative inhibitor<br /> | **[[5ai9]] – hSEH + phenol derivative inhibitor<br /> | ||
**[[5aia]], [[5mwa]] – hSEH + benzoate derivative inhibitor<br /> | **[[5aia]], [[5mwa]] – hSEH + benzoate derivative inhibitor<br /> | ||
**[[5ak3]] – hSEH + indan-amine derivative inhibitor<br /> | **[[5ak3]] – hSEH + indan-amine derivative inhibitor<br /> | ||
**[[6hgw]] – hSEH + ethanamine derivative inhibitor<br /> | |||
**[[5all]] – hSEH + cyclohexyl methanol inhibitor<br /> | **[[5all]] – hSEH + cyclohexyl methanol inhibitor<br /> | ||
**[[6i5g]] – hSEH C terminal + prostaglandin derivative<br /> | **[[6i5g]] – hSEH C terminal + prostaglandin derivative<br /> | ||
**[[1cr6]], [[1ek1]], [[1ek2]] – mSEH + urea derivative inhibitor<br /> | |||
**[[4o08]] – BmSEH + phenoxy acetamide inhibitor<br /> | **[[4o08]] – BmSEH + phenoxy acetamide inhibitor<br /> | ||
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*Limonene-1,2-epoxide hydrolase | *Limonene-1,2-epoxide hydrolase | ||
**[[1nww]] – | **[[1nww]] – ReLEH – ''Rhodococcus erythropolis''<br /> | ||
**[[4r9k]], [[4r9l]], [[4xbx]], [[4xdw]], [[5cf1]], [[5cf2]], [[5jpp]], [[5gkw]] – | **[[4r9k]], [[4r9l]], [[4xbx]], [[4xdw]], [[5cf1]], [[5cf2]], [[5jpp]], [[5gkw]], [[7vwd]], [[7vwm]], [[7vx2]] – ReLEH (mutant)<br /> | ||
**[[1nu3]] – | **[[1nu3]] – ReLEH + valpromide <br /> | ||
**[[4xbt]], [[4xdv]], [[5clk]], [[5jpu]], [[5yao]] – | **[[4xbt]], [[4xdv]], [[5clk]], [[5jpu]], [[5yao]] – ReLEH (mutant) + hexane derivative<br /> | ||
**[[4xby]], [[5ck6]], [[5yng]], [[5yqt]] – | **[[4xby]], [[5ck6]], [[5yng]], [[5yqt]] – ReLEH (mutant) + cyclopentene oxide<br /> | ||
**[[5aif]], [[5aih]], [[5aii]] – | **[[7xee]] – ReLEH (mutant) + ethanamide derivative<br /> | ||
**[[5aig]] – | **[[7xef]] – ReLEH (mutant) + pyrrolidine derivative<br /> | ||
**[[5aif]], [[5aih]], [[5aii]] – mlLEH – metagenomic library<br /> | |||
**[[5aig]] – mlLEH + valpromide <br /> | |||
}} | }} | ||
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