1amt: Difference between revisions

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-[[Image:1amt.jpg|left|200px]]
-<!--
+==Crystal structure of alamethicin at 1.5 angstrom resolution==
-The line below this paragraph, containing "STRUCTURE_1amt", creates the "Structure Box" on the page.
+<StructureSection load='1amt' size='340' side='right'caption='[[1amt]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1amt]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Trichoderma_viride Trichoderma viride]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AMT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1AMT FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=AIB:ALPHA-AMINOISOBUTYRIC+ACID'>AIB</scene>, <scene name='pdbligand=CCN:ACETONITRILE'>CCN</scene>, <scene name='pdbligand=MOH:METHANOL'>MOH</scene>, <scene name='pdbligand=PHL:L-PHENYLALANINOL'>PHL</scene>, <scene name='pdbligand=PRD_000163:Alamethicin'>PRD_000163</scene></td></tr>
--->
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1amt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1amt OCA], [https://pdbe.org/1amt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1amt RCSB], [https://www.ebi.ac.uk/pdbsum/1amt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1amt ProSAT]</span></td></tr>
-{{STRUCTURE_1amt|  PDB=1amt  |  SCENE=  }}
+</table>
+<div style="background-color:#fffaf0;">
-'''A VOLTAGE-GATED ION CHANNEL MODEL INFERRED FROM THE CRYSTAL STRUCTURE OF ALAMETHICIN AT 1.5-ANGSTROMS RESOLUTION'''
+== Publication Abstract from PubMed ==
-==Overview==
 The crystal structure of alamethicin in nonaqueous solvent has been determined, and refined at 1.5-A resolution. The molecular conformation of the three crystallographically independent molecules is largely alpha-helical with a bend in the helix axis at an internal proline residue. The helix structure is highly amphipathic as most of the solvent-accessible polar atoms lie on a narrow strip of surface parallel to the helix axis. Molecular models for the voltage-gated ion channel, with n-fold symmetry and based on the molecular conformations observed in the crystal, are characterized by strong surface complementarity, a hydrophilic interior and a hydrophobic exterior. The channel structures are stabilized by a hydrated annulus of hydrogen-bonded glutamine residues which produce the greatest restriction in the channel diameter.
-==About this Structure==
+A voltage-gated ion channel model inferred from the crystal structure of alamethicin at 1.5-A resolution.,Fox RO Jr, Richards FM Nature. 1982 Nov 25;300(5890):325-30. PMID:6292726<ref>PMID:6292726</ref>
-Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AMT OCA].
-==Reference==
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-A voltage-gated ion channel model inferred from the crystal structure of alamethicin at 1.5-A resolution., Fox RO Jr, Richards FM, Nature. 1982 Nov 25;300(5890):325-30. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/6292726 6292726]
+</div>
-[[Category: Fox, R O.]]
+<div class="pdbe-citations 1amt" style="background-color:#fffaf0;"></div>
-[[Category: Richards, F M.]]
+== References ==
-[[Category: Peptide antibiotic]]
+<references/>
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 10:27:48 2008''
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Trichoderma viride]]
+[[Category: Fox RO]]
+[[Category: Richards FM]]