4o1x: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 4o1x is ON HOLD
+==Crystal structure of human thymidylate synthase double mutant C195S-Y202C==
+<StructureSection load='4o1x' size='340' side='right'caption='[[4o1x]], [[Resolution|resolution]] 2.32&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4o1x]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O1X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4O1X FirstGlance]. <br>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SCH:S-METHYL-THIO-CYSTEINE'>SCH</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4o1x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o1x OCA], [https://pdbe.org/4o1x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4o1x RCSB], [https://www.ebi.ac.uk/pdbsum/4o1x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4o1x ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/TYSY_HUMAN TYSY_HUMAN] Contributes to the de novo mitochondrial thymidylate biosynthesis pathway.<ref>PMID:21876188</ref>
-Authors: Pozzi, C., Mangani, S.
+==See Also==
+*[[Thymidylate synthase 3D structures|Thymidylate synthase 3D structures]]
-Description: Crystal structure of human thymidylate synthase double mutant C195S-Y202C
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Mangani S]]
+[[Category: Pozzi C]]