8bxx: Difference between revisions
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==Crystal structure of formate dehydrogenase FDH2 enzyme from Granulicella mallensis MP5ACTX8 in complex with NAD and azide.== | |||
<StructureSection load='8bxx' size='340' side='right'caption='[[8bxx]], [[Resolution|resolution]] 1.97Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8bxx]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Granulicella_mallensis_MP5ACTX8 Granulicella mallensis MP5ACTX8]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=6t8j 6t8j]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8BXX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8BXX FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AZI:AZIDE+ION'>AZI</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8bxx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8bxx OCA], [https://pdbe.org/8bxx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8bxx RCSB], [https://www.ebi.ac.uk/pdbsum/8bxx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8bxx ProSAT]</span></td></tr> | ||
[[Category: Bergantino | </table> | ||
[[Category: | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/G8NTI5_GRAMM G8NTI5_GRAMM] Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms.[HAMAP-Rule:MF_03210] | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: Granulicella mallensis MP5ACTX8]] | |||
[[Category: Large Structures]] | |||
[[Category: Bergantino B]] | |||
[[Category: Cendron L]] | |||
[[Category: Filippini F]] | |||
[[Category: Robescu MS]] | |||
[[Category: Rubini R]] | |||
Latest revision as of 10:09, 18 January 2023
Crystal structure of formate dehydrogenase FDH2 enzyme from Granulicella mallensis MP5ACTX8 in complex with NAD and azide.Crystal structure of formate dehydrogenase FDH2 enzyme from Granulicella mallensis MP5ACTX8 in complex with NAD and azide.
Structural highlights
FunctionG8NTI5_GRAMM Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms.[HAMAP-Rule:MF_03210] |
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