4msw: Difference between revisions

<StructureSection load='4msw' size='340' side='right'caption='[[4msw]], [[Resolution|resolution]] 2.06&Aring;' scene=''>

<table><tr><td colspan='2'>[[4msw]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Streptomyces_lividans Streptomyces lividans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MSW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MSW FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DGA:DIACYL+GLYCEROL'>DGA</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=TYF:(2S)-2-HYDROXY-3-(4-HYDROXYPHENYL)PROPANOIC+ACID'>TYF</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4msw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4msw OCA], [https://pdbe.org/4msw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4msw RCSB], [https://www.ebi.ac.uk/pdbsum/4msw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4msw ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/KCSA_STRLI KCSA_STRLI] Acts as a pH-gated potassium ion channel; changing the cytosolic pH from 7 to 4 opens the channel, although it is not clear if this is the physiological stimulus for channel opening. Monovalent cation preference is K(+) > Rb(+) > NH4(+) >> Na(+) > Li(+).<ref>PMID:7489706</ref>  

*[[3D structures of non-human antibody|3D structures of non-human antibody]]

[[Category: Large Structures]]

[[Category: Mus musculus]]

[[Category: Streptomyces lividans]]

[[Category: Matulef K]]

[[Category: Valiyaveetil FI]]