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==Crystal Structure of FUS-1 (OXA-85), a Class D beta-lactamase from Fusobacterium nucleatum subsp. polymorphum==
==Crystal Structure of FUS-1 (OXA-85), a Class D beta-lactamase from Fusobacterium nucleatum subsp. polymorphum==
<StructureSection load='4ied' size='340' side='right' caption='[[4ied]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
<StructureSection load='4ied' size='340' side='right'caption='[[4ied]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4ied]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"fusobacterium_polymorphum"_knorr_1922 "fusobacterium polymorphum" knorr 1922]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IED OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4IED FirstGlance]. <br>
<table><tr><td colspan='2'>[[4ied]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Fusobacterium_nucleatum_subsp._polymorphum Fusobacterium nucleatum subsp. polymorphum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IED OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4IED FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ied FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ied OCA], [https://pdbe.org/4ied PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ied RCSB], [https://www.ebi.ac.uk/pdbsum/4ied PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ied ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">fus1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=76857 "Fusobacterium polymorphum" Knorr 1922])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ied FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ied OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ied RCSB], [http://www.ebi.ac.uk/pdbsum/4ied PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q6XL56_FUSNU Q6XL56_FUSNU]


==See Also==
==See Also==
*[[Beta-lactamase|Beta-lactamase]]
*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Fusobacterium polymorphum knorr 1922]]
[[Category: Fusobacterium nucleatum subsp. polymorphum]]
[[Category: Beta-lactamase]]
[[Category: Large Structures]]
[[Category: Benvenuti, M]]
[[Category: Benvenuti M]]
[[Category: Docquier, J D]]
[[Category: Docquier JD]]
[[Category: Mangani, S]]
[[Category: Mangani S]]
[[Category: Antibiotic]]
[[Category: Beta lactamase activity]]
[[Category: Beta-lactamase fold]]
[[Category: Class d beta-lactamase]]
[[Category: Fus-1]]
[[Category: Hydrolase]]
[[Category: Oxa-85]]

Latest revision as of 12:04, 9 November 2022

Crystal Structure of FUS-1 (OXA-85), a Class D beta-lactamase from Fusobacterium nucleatum subsp. polymorphumCrystal Structure of FUS-1 (OXA-85), a Class D beta-lactamase from Fusobacterium nucleatum subsp. polymorphum

Structural highlights

4ied is a 4 chain structure with sequence from Fusobacterium nucleatum subsp. polymorphum. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, , , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

Q6XL56_FUSNU

See Also

4ied, resolution 1.50Å

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