Apoptotic protease-activating factor: Difference between revisions

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 == Function ==
-'''Apoptosis protease-activating factor-1''' (APAF-1) binds to cytochrome c and ATP to form the apoptosome which leads to the recruitment and activation of caspase 9 by cleaving the procaspase 9.  Caspase 9 is involved in executing the apoptosis of cells<ref>PMID:15829969</ref>.
+'''Apoptosis protease-activating factor-1''' or '''Apoptosis peptidase-activating factor-1''' (APAF-1) binds to cytochrome c and ATP to form the apoptosome which leads to the recruitment and activation of caspase 9 by cleaving the procaspase 9.  Caspase 9 is involved in executing the apoptosis of cells<ref>PMID:15829969</ref>.
 == Disease ==
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 </StructureSection>
-==3D structures of apoptotic protease-activating factor-1==
-Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
-[[2ygs]], [[1cy5]], [[2p1h]] – hAPAF-1 CARD domain – human  <br />
-[[1c15]], [[1cww]] – hAPAF-1 CARD domain – NMR  <br />
-[[1z6t]] – hAPAF-1 + ADP   <br />
-[[3ygs]] – hAPAF-1 CARD domain + procaspase 9  <br />
-[[4rhw]], [[5wvc]] – hAPAF-1 CARD domain + caspase 9  <br />
-[[3j2t]], [[3jbt]] – hAPAF-1 + cytochrome c<br />
-[[5juy]], [[5wve]] – hAPAF-1 + caspase 9 + cytochrome c<br />
-[[3sfz]] – mAPAF-1 + ADP - mouse  <br />
-[[3shf]] – mAPAF-1 (mutant) + ADP  <br />
 == References ==
 <references/>
 [[Category:Topic Page]]