4eq8: Difference between revisions
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==Crystal structure of PA1844 from Pseudomonas aeruginosa PAO1== | ==Crystal structure of PA1844 from Pseudomonas aeruginosa PAO1== | ||
<StructureSection load='4eq8' size='340' side='right' caption='[[4eq8]], [[Resolution|resolution]] 1.39Å' scene=''> | <StructureSection load='4eq8' size='340' side='right'caption='[[4eq8]], [[Resolution|resolution]] 1.39Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4eq8]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4eq8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EQ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EQ8 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4eq8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eq8 OCA], [https://pdbe.org/4eq8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4eq8 RCSB], [https://www.ebi.ac.uk/pdbsum/4eq8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4eq8 ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/TSE1_PSEAE TSE1_PSEAE] Toxin secreted by the H1 type VI (H1-T6SS) secretion system into the periplasm of recipient cells. Degrades peptidoglycan via amidase activity thereby helping itself to compete with other bacteria (PubMed:21776080, PubMed:22931054, PubMed:22813741, PubMed:22700987). To protect itself, the bacterium synthesizes immunity protein Tsi1 that specifically interacts with and inactivates cognate toxin (PubMed:21776080, PubMed:22931054, PubMed:22700987).<ref>PMID:21776080</ref> <ref>PMID:22700987</ref> <ref>PMID:22813741</ref> <ref>PMID:22931054</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Gu | [[Category: Pseudomonas aeruginosa PAO1]] | ||
[[Category: Li | [[Category: Gu L]] | ||
[[Category: Liu | [[Category: Li N]] | ||
[[Category: Lu | [[Category: Liu X]] | ||
[[Category: Shang | [[Category: Lu D]] | ||
[[Category: Xu | [[Category: Shang G]] | ||
[[Category: Yu | [[Category: Xu S]] | ||
[[Category: Zhang | [[Category: Yu Q]] | ||
[[Category: Zhao | [[Category: Zhang J]] | ||
[[Category: Zhao Y]] | |||