7wkd: Difference between revisions

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'''Unreleased structure'''


The entry 7wkd is ON HOLD
==TRH-TRHR G protein complex==
 
<StructureSection load='7wkd' size='340' side='right'caption='[[7wkd]], [[Resolution|resolution]] 3.01&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[7wkd]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7WKD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7WKD FirstGlance]. <br>
Description:  
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LPD:L-PROLINAMIDE'>LPD</scene>, <scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7wkd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7wkd OCA], [https://pdbe.org/7wkd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7wkd RCSB], [https://www.ebi.ac.uk/pdbsum/7wkd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7wkd ProSAT]</span></td></tr>
</table>
== Function ==
[[https://www.uniprot.org/uniprot/GBB1_HUMAN GBB1_HUMAN]] Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.<ref>PMID:18611381</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Synthetic construct]]
[[Category: Cai H]]
[[Category: Cheng X]]
[[Category: He X]]
[[Category: Jiang H]]
[[Category: Jiang Y]]
[[Category: Xu HE]]
[[Category: Xu Y]]
[[Category: You C]]
[[Category: Yuan Q]]

Latest revision as of 10:05, 14 September 2022

TRH-TRHR G protein complexTRH-TRHR G protein complex

Structural highlights

7wkd is a 6 chain structure with sequence from Homo sapiens and Synthetic construct. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[GBB1_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.[1]

References

  1. ↑ Johnston CA, Kimple AJ, Giguere PM, Siderovski DP. Structure of the parathyroid hormone receptor C terminus bound to the G-protein dimer Gbeta1gamma2. Structure. 2008 Jul;16(7):1086-94. PMID:18611381 doi:http://dx.doi.org/10.1016/j.str.2008.04.010

7wkd, resolution 3.01Å

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OCA
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