7sk2: Difference between revisions
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The entry | ==Human wildtype GABA reuptake transporter 1 in complex with tiagabine, inward-open conformation== | ||
<StructureSection load='7sk2' size='340' side='right'caption='[[7sk2]], [[Resolution|resolution]] 3.82Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7sk2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7SK2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7SK2 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TGI:Tiagabine'>TGI</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7sk2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7sk2 OCA], [https://pdbe.org/7sk2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7sk2 RCSB], [https://www.ebi.ac.uk/pdbsum/7sk2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7sk2 ProSAT]</span></td></tr> | ||
</table> | |||
== Disease == | |||
[[https://www.uniprot.org/uniprot/SC6A1_HUMAN SC6A1_HUMAN]] Myoclonic-astatic epilepsy. The disease is caused by variants affecting the gene represented in this entry. | |||
== Function == | |||
[[https://www.uniprot.org/uniprot/SC6A1_HUMAN SC6A1_HUMAN]] Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Aduri NG]] | |||
[[Category: Cherezov V]] | |||
[[Category: Gati C]] | |||
[[Category: Han GW]] | |||
[[Category: Motiwala Z]] | |||
[[Category: Shaye H]] | |||