7fer: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
==== | ==Cryo-EM structure of BsClpP-ADEP1 complex at pH 4.2== | ||
<StructureSection load='7fer' size='340' side='right'caption='[[7fer]]' scene=''> | <StructureSection load='7fer' size='340' side='right'caption='[[7fer]], [[Resolution|resolution]] 3.40Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | <table><tr><td colspan='2'>[[7fer]] is a 28 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7FER OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7FER FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7fer FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7fer OCA], [https://pdbe.org/7fer PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7fer RCSB], [https://www.ebi.ac.uk/pdbsum/7fer PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7fer ProSAT]</span></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MAA:N-METHYL-L-ALANINE'>MAA</scene>, <scene name='pdbligand=MP8:(4R)-4-METHYL-L-PROLINE'>MP8</scene>, <scene name='pdbligand=OTT:(2E,4E,6E)-OCTA-2,4,6-TRIENOIC+ACID'>OTT</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7fer FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7fer OCA], [https://pdbe.org/7fer PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7fer RCSB], [https://www.ebi.ac.uk/pdbsum/7fer PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7fer ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[[https://www.uniprot.org/uniprot/CLPP_BACSU CLPP_BACSU]] Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity). ClpXP is involved in the complete degradation of the Site-2 clipped anti-sigma-W factor RsiW. This results in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor.<ref>PMID:16899079</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Bacillus subtilis]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Synthetic construct]] | ||
[[Category: Brotz-Oesterhelt H]] | |||
[[Category: Kim H]] | |||
[[Category: Kim L]] | |||
[[Category: Kim MK]] | |||
[[Category: Kwon DH]] | |||
[[Category: Lee B-G]] | |||
[[Category: Roh S-H]] | |||
[[Category: Song HK]] | |||
Latest revision as of 08:22, 8 September 2022
Cryo-EM structure of BsClpP-ADEP1 complex at pH 4.2Cryo-EM structure of BsClpP-ADEP1 complex at pH 4.2
Structural highlights
Function[CLPP_BACSU] Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity). ClpXP is involved in the complete degradation of the Site-2 clipped anti-sigma-W factor RsiW. This results in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor.[1] References |
| ||||||||||||||||