4arr: Difference between revisions
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==Crystal structure of the N-terminal domain of Drosophila Toll receptor with the magic triangle I3C== | ==Crystal structure of the N-terminal domain of Drosophila Toll receptor with the magic triangle I3C== | ||
<StructureSection load='4arr' size='340' side='right' caption='[[4arr]], [[Resolution|resolution]] 3.00Å' scene=''> | <StructureSection load='4arr' size='340' side='right'caption='[[4arr]], [[Resolution|resolution]] 3.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4arr]] is a 2 chain structure | <table><tr><td colspan='2'>[[4arr]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ARR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ARR FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=I3C:5-AMINO-2,4,6-TRIIODOBENZENE-1,3-DICARBOXYLIC+ACID'>I3C</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=I3C:5-AMINO-2,4,6-TRIIODOBENZENE-1,3-DICARBOXYLIC+ACID'>I3C</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4arn|4arn]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[4arn|4arn]]</div></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4arr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4arr OCA], [https://pdbe.org/4arr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4arr RCSB], [https://www.ebi.ac.uk/pdbsum/4arr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4arr ProSAT]</span></td></tr> | ||
</table> | </table> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 4arr" style="background-color:#fffaf0;"></div> | |||
==See Also== | |||
*[[Variable lymphocyte receptor 3D structures|Variable lymphocyte receptor 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Gangloff, M]] | [[Category: Gangloff, M]] | ||
[[Category: Gay, N J]] | [[Category: Gay, N J]] | ||
Latest revision as of 08:44, 25 August 2022
Crystal structure of the N-terminal domain of Drosophila Toll receptor with the magic triangle I3CCrystal structure of the N-terminal domain of Drosophila Toll receptor with the magic triangle I3C
Structural highlights
Publication Abstract from PubMedGenerating high-quality crystals remains a bottleneck in biological and materials sciences. Here a counter-diffusion method was used to improve the X-ray diffraction quality of the N-terminal domain of Drosophila melanogaster Toll receptor crystals. It was observed that crystallization occurred with a peculiar pattern along the capillary resembling Liesegang bands; this phenomenon is described at both macroscopic and atomic levels. It was found that bands appeared for native protein as well as for co-crystals of magic triangle (I3C)-bound protein even though they crystallize in different space groups. Crystallization occurred with a linear recurrence independent of the precipitant concentration and a protein-specific spacing coefficient. Bandwidth varied along the capillary, oscillating between large precipitation areas and single crystals. The reported data suggest that repetitive patterns can be generated with biological macromolecules in the presence of sodium malonate as a crystallization agent. A comparison with typical Liesegang patterns and the possible mechanism underlying this phenomenon are discussed. Liesegang-like patterns of Toll crystals grown in gel.,Gangloff M, Moreno A, Gay NJ J Appl Crystallogr. 2013 Apr 1;46(Pt 2):337-345. Epub 2013 Feb 14. PMID:23596340[1] From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. See AlsoReferences
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