Syntenin: Difference between revisions

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<StructureSection load='1ybo' size='340' side='right' caption='Human syntenin PDZ1+PDZ2 domains (grey and green) complex with syndecan-4 peptide (pink and yellow) (PDB id [[1ybo]]) ' scene=''>
<StructureSection load='1ybo' size='340' side='right' caption='Human syntenin PDZ1+PDZ2 domains (deep sky blue and green) complex with syndecan-4 peptide (pink and yellow) (PDB id [[1ybo]]) ' scene='91/916387/Cv/1'>


== Function ==
== Function ==
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== Structural highlights ==
== Structural highlights ==


The 3D structure of the complex of SYNT PDZ1 and PDZ2 domains with a syndecan peptide shows the simultaneous binding to the two domains<ref>PMID:16533050</ref>. The peptide forms a β strand which runs antiparallel to the PDZ β strand.
The 3D structure of the complex of SYNT PDZ1 and PDZ2 domains with a syndecan peptide shows the <scene name='91/916387/Cv/2'>simultaneous binding to the two domains</scene><ref>PMID:16533050</ref>. The peptide forms a β strand which runs antiparallel to the PDZ β strand. <scene name='91/916387/Cv/4'>Syntenin/Syndecan peptide inreactions</scene>. Water molecules are shown as red spheres.


==Syntenin 3D structures==
==Syntenin 3D structures==
[[3D structures of syntenin]]
[[3D structures of syntenin]]


Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky