Siroheme synthase: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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+<StructureSection load='6p5z' size='340' side='right' caption='Salmonella typhimurium siroheme synthase complex with Co-sirohydrochlorin, SAH and Cl- ion (PDB code [[6p5z]]) ' scene='91/915831/Cv/2'>
-<StructureSection load='6p5z' size='340' side='right' caption='Salmonella typhimurium siroheme synthase complex withCo-sirohydrochlorin, SAH and Cl- ion (PDB code [[6p5z]]) ' scene=''>
-This is a default text for your page '''Siroheme synthase'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.
-You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.
 == Function ==
-== Disease ==
+'''Siroheme synthase''' (CysG) catalyzes the reduction of sulfite to sulfide or nitrite to ammonia<ref>PMId:32054833</ref>.  CysG substrate is a tetrapyrrole.
-== Relevance ==
 == Structural highlights ==
-This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
+The tetrapyrrole in siroheme is heavily negatively charged because of the 8 acetyl and propionyl carboxylates at the corners of the siroheme and it interacts with <scene name='91/915831/Cv/6'>residues of subunits A and B</scene>. Five of these residues are positively charged <scene name='91/915831/Cv/7'>Arg and Lys residues</scene>.
 </StructureSection>
+==Siroheme synthase 3D structures==
+Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
+[[1pjq]] – StCysG + SAH – ''Salmonella typhimurium''<BR />
+[[1pjt]], [[6p7c]], [[6p7d]], [[6pqz]], [[6pr0]], [[6pr1]], [[6pr2]], [[6pr3]], [[6pr4]], [[6ulu]] – StCysG (mutant) + SAH <BR />
+[[6p5z]] – StCysG + SAH + Co-sirohydrochlorin <BR />
+[[1pjs]] – StCysG + SAH + NAD <BR />
+[[6p5x]] – StCysG (mutant) + SAH + substrate<BR />
+[[6veb]] – StCysG (mutant) + SAH + NAD + pecorrin<BR />
 == References ==
 <references/>
+[[Category:Topic Page]]