UMP/CMP kinase: Difference between revisions
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<StructureSection load='1tev' size='350' side='right' caption='Structure of human UMP/CMP kinase complex with sulfate (PDB entry [[1tev]])' scene=''> | <StructureSection load='1tev' size='350' side='right' caption='Structure of human UMP/CMP kinase complex with sulfate (PDB entry [[1tev]])' scene='69/698098/Cv/1'> | ||
== Function == | == Function == | ||
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== Relevance == | == Relevance == | ||
Several cytidine and deoxycytidine analogs are important anticancer and antiviral drugs. These drugs require stepwise phosphorylation to exert their fully therapeutic effect. This phosphorylation is done by UCK<ref>PMID:11912132</ref>. | |||
</StructureSection> | </StructureSection> | ||
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
[[1tev]], [[7e9v]] – UCK – human <br /> | |||
[[2ukd]], [[3ukd]], [[1qf9]], [[5ukd]] – smUCK + ADP + CMP – slime mold <br /> | [[2ukd]], [[3ukd]], [[1qf9]], [[5ukd]] – smUCK + ADP + CMP – slime mold <br /> | ||
[[4ukd]] – smUCK + ADP + UDP <br /> | [[4ukd]] – smUCK + ADP + UDP <br /> | ||
[[1uke]] – smUCK + inhibitor<br /> | [[1uke]] – smUCK + inhibitor<br /> | ||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||