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| == Relevance == | | == Relevance == |
| Overexpression of RBX1 contributes to tumor progression and poor prognosis of non-muscle-invasive bladder transitional cell carcinoma<ref>PMID:23609182</ref>. RBX1 and RBX2 are overexpressed in multiple human cancer tissues and required for the growth and survival of cancer cells<ref>PMID:2102004</ref>. | | Overexpression of RBX1 contributes to tumor progression and poor prognosis of non-muscle-invasive bladder transitional cell carcinoma<ref>PMID:23609182</ref>. RBX1 and RBX2 are overexpressed in multiple human cancer tissues and required for the growth and survival of cancer cells<ref>PMID:21103004</ref>. |
| </StructureSection> | | </StructureSection> |
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| == 3D Structures of RING box protein == | | == 3D Structures of RING box protein == |
| | [[Ring box protein 3D structures]] |
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| Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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| {{#tree:id=OrganizedByTopic|openlevels=0|
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| *Ring box protein 1
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| **[[2lgv]] – hRBX1 residues 12-108 (mutant) – human - NMR <br />
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| **[[1ldj]] – hRBX1 + hCullin-1 <br />
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| **[[3rtr]] – hRBX1 + hCullin-1 residues 411-766 (mutant) <br />
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| **[[1ldk]] – hRBX1 + hCullin-1 + cyclin A/Cdk2-asociated protein + Skp2-like protein <br />
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| **[[1u6g]] – hRBX1 + hCullin-1 + TIP120 protein <br />
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| **[[4f52]] – hRBX1 + hCullin-1 residues 411-690 (mutant) + glomulin<br />
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| **[[4p5o]] – hRBX1 + hCullin-1 residues 411-776 + Dcn1-like protein + NEDD8-conjugating enzyme Ubc12 + NEDD8-conjugating enzyme Ubc12 + NEDD8 <br />
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| **[[2hye]] – hRBX1 + hCullin-4A + DNA damage-binding protein 1 + nonstructural protein <br />
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| **[[4a0k]] – hRBX1 + hCullin-4A + DNA damage-binding protein 1 + DNA damage-binding protein 2 + DNA<br />
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| **[[3dpl]] – hRBX1 + hCullin-5 residues 401-780 (mutant) <br />
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| **[[3dqv]] – hRBX1 + hCullin-5 residues 401-780 (mutant) + NEDD8 <br />
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| **[[4a0c]] – hRBX1 + hCullin-4B residues 192-913 + Cullin-associated NEDD8-dissociated protein <br />
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| **[[4a0l]] – hRBX1 + hCullin-4B + DNA damage-binding protein 1 + DNA damage-binding protein 2 + DNA<br />
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| *Ring box protein 2
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| **[[2ecl]] – hRBX2 RING domain - NMR <br />
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| }}
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| == References == | | == References == |
| <references/> | | <references/> |
| | [[Category:Topic Page]] |