2mhb: Difference between revisions

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-[[Image:2mhb.gif|left|200px]]
- {{Structure
+==THE STRUCTURE OF HORSE METHAEMOGLOBIN AT 2.0 ANGSTROMS RESOLUTION==
-|PDB= 2mhb |SIZE=350|CAPTION= <scene name='initialview01'>2mhb</scene>, resolution 2.0&Aring;
+<StructureSection load='2mhb' size='340' side='right'caption='[[2mhb]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-|SITE=
+== Structural highlights ==
-|LIGAND= <scene name='pdbligand=HEM:PROTOPORPHYRIN IX CONTAINING FE'>HEM</scene>
+<table><tr><td colspan='2'>[[2mhb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1mhb 1mhb]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MHB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MHB FirstGlance]. <br>
-|ACTIVITY=
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
-|GENE=
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mhb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mhb OCA], [https://pdbe.org/2mhb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mhb RCSB], [https://www.ebi.ac.uk/pdbsum/2mhb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mhb ProSAT]</span></td></tr>
-}}
+</table>
+== Function ==
+[[https://www.uniprot.org/uniprot/HBA_HORSE HBA_HORSE]] Involved in oxygen transport from the lung to the various peripheral tissues. [[https://www.uniprot.org/uniprot/HBB_HORSE HBB_HORSE]] Involved in oxygen transport from the lung to the various peripheral tissues.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mh/2mhb_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2mhb ConSurf].
+<div style="clear:both"></div>
-'''THE STRUCTURE OF HORSE METHAEMOGLOBIN AT 2.0 ANGSTROMS RESOLUTION'''
+==See Also==
+*[[Hemoglobin 3D structures|Hemoglobin 3D structures]]
+__TOC__
-==About this Structure==
+</StructureSection>
-MHB is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. This structure supersedes the now removed PDB entry 1MHB. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MHB OCA].
-==Reference==
-The structure of horse methaemoglobin at 2-0 A resolution., Ladner RC, Heidner EJ, Perutz MF, J Mol Biol. 1977 Aug 15;114(3):385-414. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/561852 561852]
 [[Category: Equus caballus]]
-[[Category: Protein complex]]
+[[Category: Large Structures]]
-[[Category: Heidner, E G.]]
+[[Category: Heidner, E G]]
-[[Category: Ladner, R C.]]
+[[Category: Ladner, R C]]
-[[Category: Perutz, M F.]]
+[[Category: Perutz, M F]]
-[[Category: HEM]]
+[[Category: Oxygen transport]]
-[[Category: oxygen transport]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:47:20 2008''