2mhb: Difference between revisions

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-[[Image:2mhb.png|left|200px]]
-{{STRUCTURE_2mhb|  PDB=2mhb  |  SCENE=  }}
+==THE STRUCTURE OF HORSE METHAEMOGLOBIN AT 2.0 ANGSTROMS RESOLUTION==
+<StructureSection load='2mhb' size='340' side='right'caption='[[2mhb]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-===THE STRUCTURE OF HORSE METHAEMOGLOBIN AT 2.0 ANGSTROMS RESOLUTION===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[2mhb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1mhb 1mhb]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MHB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MHB FirstGlance]. <br>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mhb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mhb OCA], [https://pdbe.org/2mhb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mhb RCSB], [https://www.ebi.ac.uk/pdbsum/2mhb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mhb ProSAT]</span></td></tr>
-[[2mhb]] is a 2 chain structure of [[Hemoglobin]] with sequence from [http://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1mhb 1mhb]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MHB OCA].
+</table>
+== Function ==
+[[https://www.uniprot.org/uniprot/HBA_HORSE HBA_HORSE]] Involved in oxygen transport from the lung to the various peripheral tissues. [[https://www.uniprot.org/uniprot/HBB_HORSE HBB_HORSE]] Involved in oxygen transport from the lung to the various peripheral tissues.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mh/2mhb_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2mhb ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Hemoglobin|Hemoglobin]]
+*[[Hemoglobin 3D structures|Hemoglobin 3D structures]]
+__TOC__
-==Reference==
+</StructureSection>
-<ref group="xtra">PMID:000561852</ref><ref group="xtra">PMID:007729532</ref><references group="xtra"/>
 [[Category: Equus caballus]]
-[[Category: Heidner, E G.]]
+[[Category: Large Structures]]
-[[Category: Ladner, R C.]]
+[[Category: Heidner, E G]]
-[[Category: Perutz, M F.]]
+[[Category: Ladner, R C]]
+[[Category: Perutz, M F]]
 [[Category: Oxygen transport]]