Purine repressor: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
The <scene name='55/554904/Cv/2'>PurP guanine co-repressor binding site includes stacking interactions as well as hydrogen bonded ones</scene>. Water molecules shown as red spheres. The DNA binding domain contains a <scene name='55/554904/Cv/3'>helix-turn-helix-loop-helix motif which interacts with the DNA major groove</scene> and a hinge helix binding to to the DNA minor groove. <scene name='55/554904/Cv/4'>Residue L54 interdigitates with the DNA central base pair</scene><ref>PMID:9278422</ref>.
The <scene name='55/554904/Cv/5'>PurP guanine co-repressor binding site includes stacking interactions as well as hydrogen bonded ones</scene>. Water molecules are shown as red spheres. The DNA binding domain contains a <scene name='55/554904/Cv/6'>helix-turn-helix-loop-helix motif which interacts with the DNA major groove</scene> and a hinge helix binding to to the DNA minor groove. <scene name='55/554904/Cv/7'>Residue L54 interdigitates with the DNA central base pair</scene><ref>PMID:9278422</ref>.
</StructureSection>
</StructureSection>


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**[[1dbq]] - EcPurR CBD + Mg - NMR<br />
**[[1dbq]] - EcPurR CBD + Mg - NMR<br />
**[[1jhz]] - EcPurR CBD (mutant) + Mg <br />
**[[1jhz]] - EcPurR CBD (mutant) + Mg <br />
**[[1o57]] - PurR - ''Bacillus subtilis''<br />
**[[1o57]] - BsPurR - ''Bacillus subtilis''<br />


*Purine repressor complex with DNA and nucleotide
*Purine repressor complex with DNA and nucleotide
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**[[2puc]], [[2puf]] - EcPurR (mutant) + DNA + guanine <br />
**[[2puc]], [[2puf]] - EcPurR (mutant) + DNA + guanine <br />
**[[1zay]] - EcPurR + DNA + hypoxanthine + di-imino-purine<br />
**[[1zay]] - EcPurR + DNA + hypoxanthine + di-imino-purine<br />
**[[7rmw]] – BsPurR + PPGPP<br />
}}
}}
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman