3cey: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
 ==Crystal structure of L3MBTL2==
-<StructureSection load='3cey' size='340' side='right' caption='[[3cey]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
+<StructureSection load='3cey' size='340' side='right'caption='[[3cey]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[3cey]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CEY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3CEY FirstGlance]. <br>
+<table><tr><td colspan='2'>[[3cey]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CEY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CEY FirstGlance]. <br>
-</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">L3MBTL2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
+</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">L3MBTL2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cey FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cey OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3cey RCSB], [http://www.ebi.ac.uk/pdbsum/3cey PDBsum]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cey FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cey OCA], [https://pdbe.org/3cey PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cey RCSB], [https://www.ebi.ac.uk/pdbsum/3cey PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cey ProSAT]</span></td></tr>
-<table>
+</table>
+== Function ==
+[[https://www.uniprot.org/uniprot/LMBL2_HUMAN LMBL2_HUMAN]] Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'.<ref>PMID:19233876</ref>
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
 Check<jmol>
    <jmolCheckbox>
-     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ce/3cey_consurf.spt"</scriptWhenChecked>
+     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ce/3cey_consurf.spt"</scriptWhenChecked>
      <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
    </jmolCheckbox>
-</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3cey ConSurf].
 <div style="clear:both"></div>
 <div style="background-color:#fffaf0;">
@@ Line 24: / Line 27: @@
 From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 </div>
+<div class="pdbe-citations 3cey" style="background-color:#fffaf0;"></div>
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Homo sapiens]]
+[[Category: Human]]
-[[Category: Allali-Hassani, A.]]
+[[Category: Large Structures]]
-[[Category: Arrowsmith, C H.]]
+[[Category: Allali-Hassani, A]]
-[[Category: Bochkarev, A.]]
+[[Category: Arrowsmith, C H]]
-[[Category: Bountra, C.]]
+[[Category: Bochkarev, A]]
-[[Category: Crombet, L.]]
+[[Category: Bountra, C]]
-[[Category: Dong, A.]]
+[[Category: Crombet, L]]
-[[Category: Edwards, A M.]]
+[[Category: Dong, A]]
-[[Category: Guo, Y.]]
+[[Category: Edwards, A M]]
-[[Category: Kozieradzki, I.]]
+[[Category: Guo, Y]]
-[[Category: Loppnau, P.]]
+[[Category: Kozieradzki, I]]
-[[Category: Mackenzie, F.]]
+[[Category: Loppnau, P]]
-[[Category: Min, J.]]
+[[Category: Mackenzie, F]]
-[[Category: Nady, N.]]
+[[Category: Min, J]]
-[[Category: Pan, P.]]
+[[Category: Nady, N]]
-[[Category: Qi, C.]]
+[[Category: Pan, P]]
-[[Category: Read, R.]]
+[[Category: Qi, C]]
-[[Category: SGC, Structural Genomics Consortium.]]
+[[Category: Read, R]]
-[[Category: Vedadi, M.]]
+[[Category: Structural genomic]]
-[[Category: Weigelt, J.]]
+[[Category: Vedadi, M]]
-[[Category: Zhu, H.]]
+[[Category: Weigelt, J]]
+[[Category: Zhu, H]]
 [[Category: Chromatin regulator]]
 [[Category: Mbt]]
@@ Line 54: / Line 59: @@
 [[Category: Nucleus]]
 [[Category: Sgc]]
-[[Category: Structural genomic]]
-[[Category: Structural genomics consortium]]
 [[Category: Transcription]]
 [[Category: Transcription regulation]]
 [[Category: Transcription regulator]]
 [[Category: Zinc-finger]]