2irp: Difference between revisions

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New page: left|200px<br /><applet load="2irp" size="350" color="white" frame="true" align="right" spinBox="true" caption="2irp, resolution 2.40Å" /> '''Crystal structure of...
 
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[[Image:2irp.gif|left|200px]]<br /><applet load="2irp" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2irp, resolution 2.40&Aring;" />
'''Crystal structure of the l-fuculose-1-phosphate aldolase (aq_1979) from aquifex aeolicus VF5'''<br />


==About this Structure==
==Crystal structure of the l-fuculose-1-phosphate aldolase (aq_1979) from aquifex aeolicus VF5==
2IRP is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus] with <scene name='pdbligand=CL:'>CL</scene> and <scene name='pdbligand=BME:'>BME</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/L-fuculose-phosphate_aldolase L-fuculose-phosphate aldolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.2.17 4.1.2.17] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IRP OCA].  
<StructureSection load='2irp' size='340' side='right'caption='[[2irp]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
[[Category: Aquifex aeolicus]]
== Structural highlights ==
<table><tr><td colspan='2'>[[2irp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquae Aquae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IRP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IRP FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/L-fuculose-phosphate_aldolase L-fuculose-phosphate aldolase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.2.17 4.1.2.17] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2irp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2irp OCA], [https://pdbe.org/2irp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2irp RCSB], [https://www.ebi.ac.uk/pdbsum/2irp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2irp ProSAT], [https://www.topsan.org/Proteins/RSGI/2irp TOPSAN]</span></td></tr>
</table>
== Function ==
[[https://www.uniprot.org/uniprot/MTNB_AQUAE MTNB_AQUAE]] Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).[HAMAP-Rule:MF_01677]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ir/2irp_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2irp ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Aquae]]
[[Category: L-fuculose-phosphate aldolase]]
[[Category: L-fuculose-phosphate aldolase]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Baba, S.]]
[[Category: Baba, S]]
[[Category: Ebihara, A.]]
[[Category: Ebihara, A]]
[[Category: Gayathri, D.]]
[[Category: Gayathri, D]]
[[Category: Jeyakanthan, J.]]
[[Category: Jeyakanthan, J]]
[[Category: Kuramitsu, S.]]
[[Category: Kuramitsu, S]]
[[Category: RSGI, RIKEN.Structural.Genomics/Proteomics.Initiative.]]
[[Category: Structural genomic]]
[[Category: Shinkai, A.]]
[[Category: Shinkai, A]]
[[Category: Shiro, Y.]]
[[Category: Shiro, Y]]
[[Category: Velmurugan, D.]]
[[Category: Velmurugan, D]]
[[Category: Yogavel, M.]]
[[Category: Yogavel, M]]
[[Category: Yokoyama, S.]]
[[Category: Yokoyama, S]]
[[Category: BME]]
[[Category: Aldehyde]]
[[Category: CL]]
[[Category: Aldolase]]
[[Category: aldehyde]]
[[Category: Enzymatic mechanism]]
[[Category: aldolase]]
[[Category: Lyase]]
[[Category: enzymatic mechanism]]
[[Category: National project on protein structural and functional analyse]]
[[Category: lyase]]
[[Category: Nppsfa]]
[[Category: national project on protein structural and functional analyses]]
[[Category: Rsgi]]
[[Category: nppsfa]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomics]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 23 11:39:27 2008''

Latest revision as of 13:31, 12 January 2022

Crystal structure of the l-fuculose-1-phosphate aldolase (aq_1979) from aquifex aeolicus VF5Crystal structure of the l-fuculose-1-phosphate aldolase (aq_1979) from aquifex aeolicus VF5

Structural highlights

2irp is a 2 chain structure with sequence from Aquae. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
NonStd Res:
Activity:L-fuculose-phosphate aldolase, with EC number 4.1.2.17
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

[MTNB_AQUAE] Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).[HAMAP-Rule:MF_01677]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

2irp, resolution 2.40Å

Drag the structure with the mouse to rotate

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OCA
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