3b93: Difference between revisions

<StructureSection load='3b93' size='340' side='right' caption='[[3b93]], [[Resolution|resolution]] 2.20&Aring;' scene=''>

<table><tr><td colspan='2'>[[3b93]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B93 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3B93 FirstGlance]. <br>

</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3b94|3b94]]</td></tr>

<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TNFSF18, AITRL, GITRL, TL6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3b93 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b93 OCA], [http://pdbe.org/3b93 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3b93 RCSB], [http://www.ebi.ac.uk/pdbsum/3b93 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3b93 ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/TNF18_HUMAN TNF18_HUMAN]] Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B.<ref>PMID:17449724</ref> <ref>PMID:18040044</ref>   

*[[Tumor necrosis factor ligand superfamily|Tumor necrosis factor ligand superfamily]]

*[[Tumor necrosis factor receptor|Tumor necrosis factor receptor]]