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==Crystal Structure of Adenylosuccinate Lyase from Plasmodium Vivax== | ==Crystal Structure of Adenylosuccinate Lyase from Plasmodium Vivax== | ||
<StructureSection load='2hvg' size='340' side='right' caption='[[2hvg]], [[Resolution|resolution]] 2.30Å' scene=''> | <StructureSection load='2hvg' size='340' side='right'caption='[[2hvg]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2hvg]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2hvg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Haemamoeba_vivax Haemamoeba vivax]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HVG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HVG FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Adenylosuccinate_lyase Adenylosuccinate lyase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.3.2.2 4.3.2.2] </span></td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hvg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hvg OCA], [https://pdbe.org/2hvg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hvg RCSB], [https://www.ebi.ac.uk/pdbsum/2hvg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hvg ProSAT]</span></td></tr> | ||
<table> | </table> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hv/2hvg_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hv/2hvg_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hvg ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 2hvg" style="background-color:#fffaf0;"></div> | |||
==See Also== | |||
*[[Adenylosuccinate lyase 3D structures|Adenylosuccinate lyase 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Adenylosuccinate lyase]] | [[Category: Adenylosuccinate lyase]] | ||
[[Category: | [[Category: Haemamoeba vivax]] | ||
[[Category: Alam, Z | [[Category: Large Structures]] | ||
[[Category: Arrowsmith, C H | [[Category: Alam, Z]] | ||
[[Category: Bochkarev, A | [[Category: Arrowsmith, C H]] | ||
[[Category: Dong, A | [[Category: Bochkarev, A]] | ||
[[Category: Edwards, A M | [[Category: Dong, A]] | ||
[[Category: Hills, T | [[Category: Edwards, A M]] | ||
[[Category: Hui, R | [[Category: Hills, T]] | ||
[[Category: Kozieradzki, I | [[Category: Hui, R]] | ||
[[Category: Lew, J | [[Category: Kozieradzki, I]] | ||
[[Category: Qiu, W | [[Category: Lew, J]] | ||
[[Category: Ren, H | [[Category: Qiu, W]] | ||
[[Category: | [[Category: Ren, H]] | ||
[[Category: Sundstrom, M | [[Category: Structural genomic]] | ||
[[Category: Vedadi, M | [[Category: Sundstrom, M]] | ||
[[Category: Wasney, G A | [[Category: Vedadi, M]] | ||
[[Category: Weigelt, J | [[Category: Wasney, G A]] | ||
[[Category: Wernimont, A K | [[Category: Weigelt, J]] | ||
[[Category: Wernimont, A K]] | |||
[[Category: Alpha helical]] | [[Category: Alpha helical]] | ||
[[Category: Lyase]] | [[Category: Lyase]] | ||
[[Category: Sgc]] | [[Category: Sgc]] | ||