Nucleosomes: Difference between revisions
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This section offers some large scenes of a nucleosome ([[1aoi]]), as determined in [http://www.mol.biol.ethz.ch/groups/richmond Tim Richmond's lab], suitable for projection in biochemistry classes. | This section offers some large scenes of a nucleosome ([[1aoi]]), as determined in [http://www.mol.biol.ethz.ch/groups/richmond Tim Richmond's lab], suitable for projection in biochemistry classes. | ||
<applet load="1aoi" size="450" color="white" frame="true" align="right" caption="1aoi, resolution 2.80Å" script="Nucleosomes/Rockets/ | <applet load="1aoi" size="450" color="white" frame="true" align="right" caption="[[1aoi]], resolution 2.80Å" script="Nucleosomes/Rockets/1" /> | ||
<big> | <big> | ||
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2. '''<scene name='Nucleosomes/Dna/3'>DNA</scene>''' | 2. '''<scene name='Nucleosomes/Dna/3'>DNA</scene>''' | ||
<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>display displayed,*:i,*:j</scriptWhenChecked> | |||
<scriptWhenUnchecked>hide hidden,*:i,*:j</scriptWhenUnchecked> | |||
<checked>true</checked> | |||
<text></text> | |||
</jmolCheckbox> | |||
</jmol> | |||
3. '''<scene name='Nucleosomes/Histones/6'>Histones</scene>''' | |||
<br> | <br> | ||
| |||
<jmol> | <jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked> | <scriptWhenChecked>display displayed,*:c,*:g</scriptWhenChecked> | ||
<scriptWhenUnchecked></scriptWhenUnchecked> | <scriptWhenUnchecked>hide hidden,*:c,*:g</scriptWhenUnchecked> | ||
<text>H2a</text> | <checked>true</checked> | ||
</jmolCheckbox> | <text></text> | ||
</jmol> | </jmolCheckbox> | ||
</jmol><big>'''<font color='red'>H2a</font>'''</big> | |||
| |||
<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>display displayed,*:d,*:h</scriptWhenChecked> | |||
<scriptWhenUnchecked>hide hidden,*:d,*:h</scriptWhenUnchecked> | |||
<checked>true</checked> | |||
<text></text> | |||
</jmolCheckbox> | |||
</jmol><big>'''<font color='orange'>H2b</font>'''</big> | |||
| | ||
<jmol> | <jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked> | <scriptWhenChecked>display displayed,*:a,*:e</scriptWhenChecked> | ||
<scriptWhenUnchecked></scriptWhenUnchecked> | <scriptWhenUnchecked>hide hidden,*:a,*:e</scriptWhenUnchecked> | ||
<text> | <checked>true</checked> | ||
<text></text> | |||
</jmolCheckbox> | </jmolCheckbox> | ||
</jmol> | </jmol><big>'''<font color='green'>H3</font>'''</big> | ||
| | ||
<jmol> | <jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked> | <scriptWhenChecked>display displayed,*:b,*:f</scriptWhenChecked> | ||
<text> | <scriptWhenUnchecked>hide hidden,*:b,*:f</scriptWhenUnchecked> | ||
<checked>true</checked> | |||
<text></text> | |||
</jmolCheckbox> | </jmolCheckbox> | ||
</jmol> | </jmol><big>'''<font color='blue'>H4</font>'''</big> | ||
4. '''<scene name='Nucleosomes/Rockets/ | 4. '''<scene name='Nucleosomes/Rockets/4'>Secondary Structure</scene>''' | ||
<ul> | <ul> | ||
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</big> | </big> | ||
<scene name='1aoi/Introduction/2'>The nucleosome core particle</scene> contains two copies of each histone <font color=tan>'''protein'''</font> (<font color=tan>'''H2A, H2B, H3, H4'''</font>) and 146 basepairs (bp) of superhelical <font color=purple>'''DNA'''</font> wrapped around this histone octamer. It represents the first order of DNA packaging in the nucleus and as such is the principal structure that determines DNA accessibility (this scene was created by David Marcey, Eran Hodis, Jaime Prilusky).<br /> | |||
Examples of [[Archaeal_Histones]] | |||
<br clear='right'> | |||
< | ==3D structures of histone== | ||
[[Histone]] | |||
==Additional Resources== | |||
For Additional Information, See: [[Nucleic Acids]] | |||
== Files for 3D printer == | |||
<i class="fas fa-cubes"></i> Nucleosome by [[User:Marius Mihasan|Marius Mihasan]] [https://3dprint.nih.gov/discover/3DPX-015090 <i class="fas fa-download"></i>] | |||
[[Category:Nucleosome]] | [[Category:Nucleosome]] | ||
[[Category:3D printer files]] | |||