Macrophage inhibitory factor: Difference between revisions
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<StructureSection load='2ooh' size='350' side='right' caption='Structure of human macrophage inhibitory factor trimer complex with inhibitor, glycerol and sulfate (PDB entry [[2ooh]])' scene='55/551208/Cv/1'> | <StructureSection load='2ooh' size='350' side='right' caption='Structure of human macrophage inhibitory factor trimer complex with inhibitor, glycerol and sulfate (PDB entry [[2ooh]])' scene='55/551208/Cv/1'> | ||
== Function == | == Function == | ||
'''Macrophage inhibitory factor''' or '''Macrophage migration inhibitory factor''' (MIF) is an inflammatory cytokine. MIF is released to the blood stream upon stimulation of white blood cells by bacterial antigens<ref>PMID:11032394</ref>. | '''Macrophage inhibitory factor''' or '''Macrophage migration inhibitory factor''' (MIF) is an inflammatory cytokine. '''MIF2''' or '''D-dopachrome tautomerase''' or '''D-dopachrome decarboxylase''' is a pro-inflammatory cytokine which regulates the innate and adaptive immune response<ref>PMID:22507380</ref>. MIF is released to the blood stream upon stimulation of white blood cells by bacterial antigens<ref>PMID:11032394</ref>. | ||
== Relevance == | == Relevance == | ||